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. 2024 Oct 17;10(10):CD015972.
doi: 10.1002/14651858.CD015972.

Risk of fracture in users of hormonal contraception

Shaalini Ramanadhan  1 , Jillian T Henderson  2 , Amy Cantor  3 , Robin A Paynter  4 , Alison Edelman  1
Affiliations

Risk of fracture in users of hormonal contraception

Shaalini Ramanadhan et al. Cochrane Database Syst Rev. .

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of hormonal contraception used for pregnancy prevention on fracture risk in individuals who are currently or were previously capable of becoming pregnant.

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Conflict of interest statement

SR: serves as a deputy editor of Cochrane Fertility Regulation Group. She was not involved in the editorial processes for this protocol.

JH: serves as the methodologist of Cochrane Fertility Regulation Group. She was not involved in the editorial processes for this protocol. Other declarations: Oregon Health & Science University (employment), Kaiser Permanente (employment).

AC: none known.

RP: none known.

AE: serves as a deputy editor of Cochrane Fertility Regulation Group. She was not involved in the editorial processes for this protocol. Other declarations: Centers for Disease Control and Prevention (Independent Contractor ‐ Expert Witness), American College of Obstetricians and Gynecologists (Independent Contractor ‐ End Point Review Committee), World Health Organization (Independent Contractor ‐ Other), Writer for different topics (Other IP).

References

    1. United Nations. Contraceptive Use by Method 2019: Data Booklet. UN Department of Economic and Social Affairs, Population Division 2019.
    1. Lopez LM, Grimes DA, Schulz KF, Curtis KM, Chen M. Steroidal contraceptives: effect on bone fractures in women. Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No: CD006033. [DOI: 10.1002/14651858.CD006033.pub5] - DOI - PubMed
    1. US Food and Drug Administration. FDA Talk Paper. Black box warning added concerning long-term use of depo-provera contraceptive injection. downloads.regulations.gov/FDA-2019-P-2289-0013/attachment_5.pdf 17 Nov 2004.
    1. Depo-Provera CI prescribing information. labeling.pfizer.com/ShowLabeling.aspx?id=522.
    1. Kaunitz AM, Grimes DA. Removing the black box warning for depot medroxyprogesterone acetate. Contraception 2011;84(3):212-3. - PubMed

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