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. 1986 Jan;319(6051):291-5.
doi: 10.1038/319291a0.

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes

F Rouyer, M C Simmler, C Johnsson, G Vergnaud, H J Cooke, J Weissenbach

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes

F Rouyer et al. Nature. 1986 Jan.

Abstract

Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.

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