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Review
. 2024 Oct;15(5):340-349.
doi: 10.14740/cr1665. Epub 2024 Sep 16.

Advances in the Understanding and Treatment of Chronic Chagas Cardiomyopathy

Jordan Llerena-Velastegui  1   2 , Almendra Lopez-Usina  1 , Camila Mantilla-Cisneros  1
Affiliations
Review

Advances in the Understanding and Treatment of Chronic Chagas Cardiomyopathy

Jordan Llerena-Velastegui et al. Cardiol Res. 2024 Oct.

Abstract

Chronic Chagas cardiomyopathy (CCC) poses significant health challenges not only in Latin America but also in non-endemic regions due to global migration. The complexity and severity of CCC call for an updated and thorough review to inform clinical practices and direct future research efforts. This review seeks to consolidate current knowledge on CCC, emphasizing diagnostic, therapeutic, and prognostic facets to facilitate better management and understanding of the disease. An exhaustive examination was conducted, analyzing peer-reviewed articles published between January 2020 and April 2024, sourced from prominent medical databases such as PubMed and Scopus. The review delineates crucial aspects of CCC pathophysiology, evaluates patient outcomes, identifies diagnostic challenges, and assesses treatment efficacy. Our findings prompt the need for revised clinical guidelines and stress the importance of continued research to enhance therapeutic strategies and disease comprehension. It is imperative that future studies address these identified gaps to advance patient care and treatment options for CCC.

Keywords: Chronic Chagas cardiomyopathy; Diagnostic challenges; Pathophysiology; Patient outcomes; Treatment efficacy.

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Conflict of interest statement

The author declares no conflict of interest to ensure the impartiality of the review.

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