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Review
. 2024 Oct 3:15:1397872.
doi: 10.3389/fphar.2024.1397872. eCollection 2024.

Enhancing health and therapeutic potential: innovations in the medicinal and pharmaceutical properties of soy bioactive compounds

Affiliations
Review

Enhancing health and therapeutic potential: innovations in the medicinal and pharmaceutical properties of soy bioactive compounds

Ubaidur Rahman et al. Front Pharmacol. .

Abstract

An extensive examination of the medical uses of soybean bioactive components is provided by this thorough review. It explores the possible health advantages of isoflavones with phytoestrogenic qualities, like genistein, which may lower the risk of cancer. The review highlights the different roles and possible anticancer activities of phenolic compounds, phytic acid, protease inhibitors, lignans, and saponins, among other bioactive components. It also addresses the benefits of dietary fiber and oligosaccharides derived from soybeans for intestinal health, as well as the impact of soy protein on diabetes, obesity, cancer, and cardiovascular health. Conjugated linoleic acid (CLA) has anticancer and cholesterol-lowering properties; its involvement in promoting metabolic processes is also examined. Pinitol is highlighted in the study as a blood sugar regulator with promise for controlling insulin signaling. In this review, we aim to affirm soybeans' potential as a high-functional, well-being food by examining their recently discovered therapeutic and pharmacological capabilities, rather than to improve upon the previous studies on the reported nutritional advantages of soybeans.

Keywords: cancer; diabetes; isoflavones; peptides; pinitol; soybean; therapeutic.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Major therapeutic bioactive compounds and disease targets of soybean.
FIGURE 2
FIGURE 2
This schematic diagram shows different pathways which indicate that the isoflavones have the therapeutic potential to induced cancer cell death.
FIGURE 3
FIGURE 3
This diagram show that Phytic acid have the therapeutic potential to decreased and control the following mentioned diseases in the figure.
FIGURE 4
FIGURE 4
This diagram indicate that protease inhibitors have some pharmacological and therapeutic activities against some diseases.
FIGURE 5
FIGURE 5
This figure explained the overall pharmaceutical and therapeutic potential of lignans against different diseases and pathogens.
FIGURE 6
FIGURE 6
This schematic diagram shows the anti-cholesterol lowering mechanism and anti-cancer mechanism of saponin derivatives at cellular levels.
FIGURE 7
FIGURE 7
This diagram indicates the anti-hypertension activity of soybean oligosaccharides and their derivatives.
FIGURE 8
FIGURE 8
Cholesterol is the main cause of many diseases such as blood pressure and cardiovascular diseases, so this schematic diagram show that soybean proteins and peptides have the potential to lower the cholesterol level in the body.
FIGURE 9
FIGURE 9
The schematic illustration of the CLA-regulated biological pathway during carcinogenic, adipose, diabatic, antioxidant, anti-inflammatory and cardiovascular diseases.
FIGURE 10
FIGURE 10
This schematic diagram show that D-pinitol have some pharmaceutical and therapeutic potential against cancer, diabetes, anti-cholesteric effects and anti-inflammatory properties.

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