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. 2025 Mar 1;120(3):675-680.
doi: 10.14309/ajg.0000000000003143. Epub 2024 Oct 18.

Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Female Patients and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021

Pojsakorn Danpanichkul  1 , Kwanjit Duangsonk  2 , Agnes H Y Ho  3 , Passisd Laoveeravat  4 , Chawinthorn Vuthithammee  5 , Disatorn Dejvajara  6 , Vitchapong Prasitsumrit  7 , Thanida Auttapracha  6 , Busara Songtanin  1 , Panu Wetwittayakhlang  8 , Rashid N Lui  3 , Gursimran Singh Kochhar  9 , Siew C Ng  3 , Francis A Farraye  10 , Karn Wijarnpreecha  11   12   13
Affiliations

Disproportionately Increasing Incidence of Inflammatory Bowel Disease in Female Patients and the Elderly: An Update Analysis from the Global Burden of Disease Study 2021

Pojsakorn Danpanichkul et al. Am J Gastroenterol. .

Abstract

Introduction: To update the global burden of inflammatory bowel disease (IBD) using data from the Global Burden of Disease 2021.

Methods: Data from Global Burden of Disease 2021 were analyzed to assess the IBD burden.

Results: In 2021, there were 375,140 new cases and 3.83 million total cases of IBD. Elderly onset IBD accounted for 11% of incidences. 167 countries increased IBD incidence rate, with rates rising in female patients (APC: +0.06%) and the elderly (APC: +0.14%) but stable in male patients and the overall population.

Discussion: Although the global burden of IBD has decreased overall, it has increased in female patients and the elderly.

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