What Are the Contraindications, if Any, for the Use of Tranexamic Acid During Knee or Hip Arthroplasty?

Affiliations

¹ Department of Orthopaedics, Nikan General Hospital, Tehran, Iran.
² Department of Orthopedics and Traumatology, Istanbul Medipol University School of Medicine, Istanbul, Turkey.
³ Department of Orthopaedics, WVU School of Medicine, Morgantown, West Virginia.
⁴ Department of Orthopedics and Traumatology, Hospital Universitario Fundación Jiménez Díaz, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.
⁵ Endocrinology and Metabolism Population Sciences Institute, Chronic Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
⁶ Department of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, Bucharest, Romania; Department of Orthopaedics and Traumatology, The "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
⁷ zanjan University of Medical Sciences, Zanjan, Iran.
⁸ Department of Radiology and Medical Imaging, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, Bucharest, Romania; Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
⁹ Medical Education Research Center, Education Development Center, Guilan University of Medical Sciences, Rasht, Iran.
¹⁰ Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

Review

Mohammadali Enayatollahi et al. J Arthroplasty. 2025 Feb.

. 2025 Feb;40(2S1):S21-S24.

doi: 10.1016/j.arth.2024.10.050. Epub 2024 Oct 18.

¹ Department of Orthopaedics, Nikan General Hospital, Tehran, Iran.
² Department of Orthopedics and Traumatology, Istanbul Medipol University School of Medicine, Istanbul, Turkey.
³ Department of Orthopaedics, WVU School of Medicine, Morgantown, West Virginia.
⁴ Department of Orthopedics and Traumatology, Hospital Universitario Fundación Jiménez Díaz, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.
⁵ Endocrinology and Metabolism Population Sciences Institute, Chronic Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
⁶ Department of Orthopaedics, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, Bucharest, Romania; Department of Orthopaedics and Traumatology, The "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
⁷ zanjan University of Medical Sciences, Zanjan, Iran.
⁸ Department of Radiology and Medical Imaging, "Foisor" Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, Bucharest, Romania; Department of Physiology, The "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
⁹ Medical Education Research Center, Education Development Center, Guilan University of Medical Sciences, Rasht, Iran.
¹⁰ Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

No abstract available

Keywords: TXA; contraindication; total hip arthroplasty; total joint arthroplasty; total knee arthroplasty; tranexamic acid.

Publication types