Considerations in Premature Menopause: A Review
- PMID: 39429402
- PMCID: PMC11490301
- DOI: 10.7759/cureus.69744
Considerations in Premature Menopause: A Review
Abstract
Premature menopause impacts 1% of women under the age of 40. The women are at risk of premature death, ischemic disease of the heart, neurological conditions, mood disturbances, psychosexual problems, osteoporosis, and subfertility. There is an imperative for less complicated protocols and enhanced approaches for oocyte donation to get pregnant and achieve motherhood in at-risk women. A review of the pertinent literature on premature ovarian insufficiency and selected references was done. A comprehensive review was undertaken by searching the databases PubMed, Scopus, EMBASE, Web of Science, and Science Direct. Pregnancy in women with premature menopause was formerly uncommon, but because of recent advances in oocyte donation, women with premature menopause can now aspire to have a child. Hormone replacement treatment is useful in treating the negative effects of premature ovarian insufficiency. Women who experience early menopause are at risk for early mortality, ischemic heart disease, neurological conditions, mood problems, psychosexual disorder, osteoporosis, and subfertility. Public awareness and education are critical tools for saving women at peril.
Keywords: bilateral oophorectomy; estrogen; induced menopause; ovarian failure; premature menopause; spontaneous menopause.
Copyright © 2024, Dave et al.
Conflict of interest statement
Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
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References
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- Incidence of premature ovarian failure. Coulam CB, Adamson SC, Annegers JF. https://pubmed.ncbi.nlm.nih.gov/3960433/ Obstet Gynecol. 1986;67:604–606. - PubMed
-
- Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. Rossouw JE, Anderson GL, Prentice RL, et al. JAMA. 2002;288:321–333. - PubMed
-
- Treatment of symptoms of the menopause: an Endocrine Society clinical practice guideline. Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH, Pinkerton JV, Santen RJ. J Clin Endocrinol Metab. 2015;100:3975–4011. - PubMed
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