Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Oct;41(10):e15945.
doi: 10.1111/echo.15945.

Echocardiography in Endocarditis

Affiliations
Review

Echocardiography in Endocarditis

Cosimo Angelo Greco et al. Echocardiography. 2024 Oct.

Abstract

Infective endocarditis (IE) continues to have high rates of adverse outcomes, despite recent advances in diagnosis and management. Although the use of computer tomography and nuclear imaging appears to be increasing, echocardiography, widely available in most centers, is the recommended initial modality of choice to diagnose and consequently guide the management of IE in a timely-dependent fashion. Echocardiographic imaging should be performed as soon as the IE diagnosis is suspected. Several factors may delay diagnosis, for example, echocardiography findings may be negative early in the disease course. Thus, repeated echocardiography is recommended in patients with negative initial echocardiography if high suspicion for IE persists in patients at high risk. However, systematic echocardiographic screening should not be utilized as a common tool for fever, but only in the presence of a reasonable clinical suspicion of IE. It may increase the risk of false-positive rates of patients requiring IE therapy or may exacerbate diagnostic uncertainty about subtle findings. Considering the complexity of the disease, the echocardiographic use should be increasingly time-efficient and should focus on the correct identification of IE lesions and associated complications. The path to identify patients who need surgery passes through an echocardiographic skill ensuring the identification of the cardiac anatomical structures and their involvement in the destructive infective extension. We pointed out the role of echocardiography focused on the correct identification of IE distinctive lesions and the associated complications, as part of a diagnostic strategy, within an integrated multimodality imaging, managed by an "endocarditis team".

Keywords: echocardiography; infective endocarditis; multimodality imaging; three‐dimensional transesophageal echocardiography.

PubMed Disclaimer

References

    1. M. J. Dayer, S. Jones, B. Prendergast, et al., “An Increase in the Incidence of Infective Endocarditis in England Since 2008: A Secular Trend Interrupted Time Series Analysis,” Lancet 385, no. 9974 (2015): 1219–1228.
    1. K. M. Talha, L. M. Baddour, M. H. Thornhill, et al., “Escalating Incidence of Infective Endocarditis in Europe in the 21st Century,” Open Heart 8, no. 2 (2021): e001846.
    1. G. Habib; P. A. Erba, B. Iung, et al., “Clinical Presentation, Aetiology and Outcome of Infective Endocarditis. Results of the ESC‐EORP EURO‐ENDO (European Infective Endocarditis) Registry: A Prospective Cohort Study,” European Heart Journal 40 (2019): 3222–3232.
    1. A. Barbieri, E. Cecchi, F. Bursi, et al., “Is Infectious Endocarditis Evolving Into a Time‐Dependent Diagnosis in the Contemporary Epidemiological Era? Emphasis on the Role of Echocardiography as a First‐Line Diagnostic Approach,” Reviews in Cardiovascular Medicine 24, no. 10 (2023): 283–293.
    1. E. Holte, M. R. Dweck, N. A. Marsan, et al., “EACVI Survey on the Evaluation of Infective Endocarditis,” European Heart Journal Cardiovascular Imaging 21 (2020): 828–832.

LinkOut - more resources