IL-23R-Specific Chimeric Antigen Receptor Tregs in Crohn's Disease: Dawn of a Cellular Immunotherapeutic Era?

Raja Atreya^{1

2}, Markus F Neurath^{1

2}

Affiliations

¹ Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
² Deutsches Zentrum Immuntherapie (DZI), Erlangen, Germany.

Editorial

Raja Atreya et al. J Crohns Colitis. 2025.

. 2025 Apr 4;19(4):jjae159.

doi: 10.1093/ecco-jcc/jjae159.

Raja Atreya^{1

2}, Markus F Neurath^{1

2}

¹ Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
² Deutsches Zentrum Immuntherapie (DZI), Erlangen, Germany.

No abstract available

Comment on

IL23R-Specific CAR Tregs for the Treatment of Crohn's Disease.
Cui Y, David M, Bouchareychas L, Rouquier S, Sajuthi S, Ayrault M, Navarin C, Lara G, Lafon A, Saviane G, Boulakirba S, Menardi A, Demory A, Frikeche J, de la Forest Divonne Beghelli S, Lu HH, Dumont C, Abel T, Fenard D, de la Rosa M, Gertner-Dardenne J. Cui Y, et al. J Crohns Colitis. 2025 Mar 5;19(3):jjae135. doi: 10.1093/ecco-jcc/jjae135. J Crohns Colitis. 2025. PMID: 39252592 Free PMC article.