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. 1986 Jan 15;42(1):77-80.
doi: 10.1007/BF01975904.

Regression of genetically determined polycystic kidney disease in murine organ culture

E D Avner, W E Sweeney Jr, N P Piesco, D Ellis

Regression of genetically determined polycystic kidney disease in murine organ culture

E D Avner et al. Experientia. .

Abstract

Cystic kidneys from the mutant CPK strain of C57BL/6J mice were cultured in serum-free organ culture. During 120 h of incubation in chemically-defined medium, CPK cystic tubular changes underwent complete regression. Environmental factors regulate the expression of genetically determined polycystic kidney disease in this model.

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References

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