Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2024 Dec;28(12):2013-2025.
doi: 10.1007/s10995-024-04006-1. Epub 2024 Oct 22.

Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis

Affiliations
Meta-Analysis

Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis

Asha P Shetty et al. Matern Child Health J. 2024 Dec.

Abstract

Background: Infants who are not exclusively breastfed are more vulnerable to gastroenteritis, respiratory illness, and type 1 diabetes mellitus. Mothers who do not breastfeed their infants are at a higher risk of cancer. This systematic review and meta-analysis aimed to synthesize evidence regarding the effectiveness of applying lanolin, aloe vera, and peppermint for alleviating nipple pain and nipple trauma among lactating mothers.

Methods: Electronic databases, including PubMed (MEDLINE), Cochrane, Cumulative Index to Nursing and Allied Health Literature (CINAHL), EMBASE, Web of Science, Scopus, and Clinical Key, were searched for studies published in English from January 2000 to December 2022. Nipple pain and nipple trauma were the primary outcomes analysed, and a meta-analysis was conducted via RevMan v5.4.

Results: The reviewed trials involved 1,495 participants from 11 studies, with an average participant age of 29 ± 5 years. The application of lanolin significantly reduced nipple pain and nipple trauma in lactating mothers. The application of peppermint significantly reduced nipple trauma in lactating mothers.

Conclusion: The application of lanolin or peppermint is a beneficial preventive intervention for reducing nipple trauma and pain.

Keywords: Aloe; Breastfeeding; Lactation; Lanolin; Menthe piperita.

PubMed Disclaimer

Conflict of interest statement

Declarations Ethical approval This review protocol has been registered with PROSPERO (CRD42023407225). Author agreement We, the undersigned, declare that this manuscript is original, has not been published before, and is not currently being considered for publication elsewhere. Competing interests No potential conflict of interest relevant to this article was reported.

References

    1. Abedi, P., Jahanfar, S., Namvar, F., & Lee, J. (2016). Breastfeeding or nipple stimulation for reducing postpartum haemorrhage in the third stage of labour. The Cochrane Database of Systematic Reviews, 2016(1). https://doi.org/10.1002/14651858.CD010845.PUB2
    1. Abou-Dakn, M., Fluhr, J. W., Gensch, M., & Wöckel, A. (2010). Positive effect of HPA Lanolin versus expressed breastmilk on painful and damaged nipples during Lactation. Skin Pharmacology and Physiology, 24(1), 27–35. https://doi.org/10.1159/000318228 - DOI - PubMed
    1. Akbari, S. A. A., Alamolhoda, S. H., Baghban, A. A., & Mirabi, P. (2014). Effects of menthol essence and breast milk on the improvement of nipple fissures in breastfeeding women. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 19(7), 629. https://pubmed.ncbi.nlm.nih.gov/25364362/ - PubMed
    1. Andersen, F. A. (2007). Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice, aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice, aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. International Journal of Toxicology, 26(Suppl 2(SUPPL), 1–50. https://doi.org/10.1080/10915810701351186 - DOI
    1. Binns, C. W., & Lee, M. K. (2014). Exclusive breastfeeding for six months: The WHO six months recommendation in the Asia Pacific Region. Asia Pacific Journal of Clinical Nutrition, 23(3), 344–350. https://doi.org/10.6133/APJCN.2014.23.3.21 - DOI - PubMed

LinkOut - more resources