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Review

Myelodysplastic Neoplasms/Syndromes (MDS)

Marie Robin  1 , Carmelo Gurnari  2   3
Anna Sureda  1 , Selim Corbacioglu  2 , Raffaella Greco  3 , Nicolaus Kröger  4 , Enric Carreras  5
, editors.
In: The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies [Internet]. 8th edition. Cham (CH): Springer; 2024. Chapter 74.
.
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Review

Myelodysplastic Neoplasms/Syndromes (MDS)

Marie Robin et al.
Free Books & Documents

Excerpt

Myelodysplastic neoplasms/syndromes (MDS) are a heterogeneous group of clonal stem cell disorders characterized by peripheral cytopenias and dysplastic features in blood and bone marrow.

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References

    1. Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka H-M, Wang SA, et al. International consensus classification of myeloid neoplasms and acute Leukemias: integrating morphologic, clinical, and genomic data. Blood. 2022;140(11):1200–28. https://doi.org/10.1182/blood.2022015850. - DOI - PMC - PubMed
    1. Bejanyan N, Zhang M, Bo-Subait K, Brunstein C, Wang H, Warlick ED, Giralt S, et al. Myeloablative conditioning for allogeneic transplantation results in superior disease-free survival for acute myelogenous leukemia and myelodysplastic syndromes with low/intermediate but not high disease risk index: a center for international blood and marrow transplant research study. Transplant Cell Ther. 2021;27(1):68.e1–9. https://doi.org/10.1016/j.bbmt.2020.09.026. - DOI - PMC - PubMed
    1. Craddock C, Labopin M, Robin M, Finke J, Chevallier P, Yakoub-Agha I, Bourhis JH, et al. Clinical activity of Azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia. Haematologica. 2016;101(7):879–83. https://doi.org/10.3324/haematol.2015.140996. - DOI - PMC - PubMed
    1. Craddock C, Jackson A, Loke J, Siddique S, Hodgkinson A, Mason J, Andrew G, et al. Augmented reduced-intensity regimen does not improve postallogeneic transplant outcomes in acute Myeloid Leukemia. J Clin Oncol. 2021;39(7):768–78. https://doi.org/10.1200/JCO.20.02308. - DOI - PMC - PubMed
    1. Cutler CS, Lee SJ, Greenberg P, Deeg HJ, Perez WS, Anasetti C, Bolwell BJ, et al. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood. 2004;104(2):579–85. - PubMed

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