Indolent Lymphoma
- PMID: 39437094
- Bookshelf ID: NBK608302
- DOI: 10.1007/978-3-031-44080-9_84
Indolent Lymphoma
Excerpt
Indolent lymphomas (iNHL) form an heterogenous group accounings for 1/3 of all malignant lymphomas with Follicular lymphoma (FL) being the most common subtype. iNHL are characterized by repeated relapses. Among available treatment lines, autologous (auto) and allogeneic (allo) HCT are the only curative options for relapsed disease. Nevertheless, the roles of both forms of HCT are evolving and are currently being challenged as T-cell engaging therapies emerge. The indications for auto-HCT and allo-HCT in 2023 are reviewed in this chapter.
Copyright 2024, The Author(s).
Sections
- 84.1. Definition and Epidemiology
- 84.2. Diagnosis
- 84.3. Prognosis
- 84.4. First Line Treatment
- 84.5. Treatment at First Relapse and Beyond
- 84.6. Autologous HCT
- 84.7. Allogeneic HCT
- 84.8. The Place of Auto- and Allo-HCT in the Therapeutic Algorithm of iNHL
- 84.9. Latest (Selected) EBMT Results
- 84.10. Conclusions
- References
References
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- Al-Hamadani M, Habermann TM, Cerhan JR, et al. Non-Hodgkin lymphoma subtype distribution, geodemographic patterns, and survival in the US: a longitudinal analysis of the National Cancer Data Base from 1998 to 2011. Am J Hematol. 2015;90(9):790–5. - PubMed
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- Avivi I, Montoto S, Canals C, et al. Matched unrelated donor stem cell transplant in 131 patients with follicular lymphoma: an analysis from the lymphoma working Party of the European Group for blood and marrow transplantation. Br J Haematol. 2009;147(5):719–28. - PubMed
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- Avivi I, Arcaini L, Ferretti VV, et al. High-dose therapy and autologous stem cell transplantation in marginal zone lymphomas: a retrospective study by the EBMT lymphoma working party and FIL-GITMO. Br J Haematol. 2018;182(6):807–15. - PubMed
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