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Case Reports
. 2024 Oct 22;24(1):465.
doi: 10.1186/s12886-024-03725-x.

Posterior short ciliary arteries ischemia following embolization of anterior ethmoid artery to treat dural arteriovenous fistulas: a case report

Yuyi Han  1 , Xiaoyong Liu  2 , Tingting Yao  1 , Qianqian Zhou  1 , Jihong Wang  3 , Chunfang Wang  4
Affiliations
Case Reports

Posterior short ciliary arteries ischemia following embolization of anterior ethmoid artery to treat dural arteriovenous fistulas: a case report

Yuyi Han et al. BMC Ophthalmol. .

Abstract

Background: The Onyx™ Liquid Embolic System is a non-adhesive liquid embolic agent, which has been proved by the US FDA for embolization of lesions in the peripheral and neurovasculature since 2005. We reported a case of ischemic optic neuropathy after using Onyx-18 to embolize the anterior ethmoid arteries that feeding dural arteriovenous fistulas (DAVF).

Case presentation: A 57-year-old Asian male presented with anterior cranial fossa DAVF underwent embolotherapy by delivering Onyx-18 through a microcatheter into the anterior ethmoid arteries under angiography guidance. The interventional procedure was successful and no clear evidence was found pointing to untargeted occlusive embolus. But after the surgery the patient experienced delayed painless vision loss in the right eye (RE). The fundoscopy showed unilateral papilledema with pale optic disc in RE, accompanied by significant edema and thickening in the retinal nerve fiber layer (RNFL) of macula. The fundus fluorescence angiography showed that most of the optic disc in RE had postponed or absent fluorescence filling. Visual evoked potential (VEP) confirmed that the amplitude of the P100 component was decreased in RE without significant prolongation of the latency. The patient was diagnosed with anterior ischemic optic neuropathy, but immediate pulse steroid therapy failed to rescue his vision.

Conclusion: Preoperative evaluation of the patient's hemodynamic status and fundus examination are essential for assessing the risk of ischemic ocular complications, and the non-adhesive liquid embolic agent Onyx-18 should be used cautiously during endovascular embolization of intracranial artery.

Keywords: Case report; DAVF; Embolization; Ischemic optic neuropathy; Onyx.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Fundus photography of RE. (A) Normal fundus appearance of RE before the interventional surgery. (B) Day 7 after surgery. The appearance of the fundus showed unilateral papilledema with pale optic disc in RE, and linear hemorrhage was seen around the vessels of the optic papilla
Fig. 2
Fig. 2
Day 7 after surgery, OCT scans of different retina locations in RE. (A) Significant papilledema. (B) and (C) Thickened RNFL and significant macular edema
Fig. 3
Fig. 3
Day 3 after surgery, fundus fluorescence angiography of RE. At the early stage, background fluorescence was partially weak in the nasal side of choroid, later most of the optic disc showed absent fluorescence filling except for the inferior temporal side
Fig. 4
Fig. 4
Day 3 after surgery, VEP showed that the amplitude of the P100 component was decreased in RE without significant prolongation of the latency
See this image and copyright information in PMC

References

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