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. 2024 Oct 23;28(1):87-93.
doi: 10.34763/jmotherandchild.20242801.d-24-00004. eCollection 2024 Feb 1.

The Impact of Undetected Hyperglycaemia During Pregnancy on Maternal and Neonatal Outcomes

Olga Olszak  1 , Jarosław Kalinka  2
Affiliations

The Impact of Undetected Hyperglycaemia During Pregnancy on Maternal and Neonatal Outcomes

Olga Olszak et al. J Mother Child. .

Abstract

Background: Despite clear diagnostic criteria for hyperglycaemia first detected in pregnancy, many pregnant women do not have the proper diagnosis. The following paper analyses the course of the perinatal period in pregnant women with undetected hyperglycaemia and their newborns.

Materials and methods: Medical data of patients hospitalized in the Department of Perinatology between 2020 and 2022 was verified: 1st group: 40 patients with undetected hyperglycaemia, 2nd group: 40 with the diagnosis of gestational diabetes during pregnancy and adequate therapeutic management. The course of the perinatal period, abnormalities in the oral glucose tolerance test (OGTT) and the compliance with recommended postpartum tests were analysed.

Results: There were significant differences in the newborn weights (p=0.039) - in the 1st group 15% large for gestational age (LGA) vs. 0% in the 2nd, and the occurrence of neonatal hyperbilirubinemia requiring phototherapy (p=0.007) - 22.5% in the 1st group vs. 2.5% in the 2nd. The most common mistake in the OGTT was evaluation of fasting plasma glucose. In the 1st group, no effect on incidence of hypertensive disorders, time or the route of delivery was observed. 75% from the 1st group and 36% from the 2nd did not perform postpartum OGTT (p=0.003).

Conclusion: Hyperglycaemia in pregnancy is often undetected, which has a negative impact, especially on the neonates. In our study, LGA and hyperbilirubinaemia were significantly more common in neonates of mothers with undetected hyperglycaemia. These women had significantly more careless attitude to the postpartum diagnostic, which may influence future health and course of subsequent pregnancies. New and more effective methods of educating practitioners need to be implemented.

Keywords: Diabetes; Gestational; Glucose Tolerance Test; Hyperglycaemia; Pregnancy.

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Figures

Figure 1.
Figure 1.
The results of the 75 g oral glucose tolerance test in the group of pregnant patients with undetected hyperglycaemia (1st group).
See this image and copyright information in PMC

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References

    1. Wender-Ożegowska E, Bomba-Opoń D, Brązert J, Celewicz Z, Czajkowski K, Gutaj P. et al. The Polish Society of Gynaecologists and Obstetricians standards for the management of patients with diabetes. Ginekol Pol. 2018;89(6):341–50. doi: 10.5603/GP.a2018.0059. - DOI - PubMed
    1. Hunger-Dathe W, Volk K, Braun A, Sämann A, Müller UA, Peiker G. et al. Perinatal morbidity in women with undiagnosed gestational diabetes in Northern Thuringia in Germany. Experimental and Clinical Endocrinology and Diabetes. 2005;113(3):160–6. doi: 10.1055/s-2005-837517. - DOI - PubMed
    1. Poolsup N, Suksomboon N, Amin M. Effect of treatment of gestational diabetes mellitus: A systematic review and meta-analysis. PLoS One. 2014;9(3):1–9. doi: 10.1371/journal.pone.0092485. - DOI - PMC - PubMed
    1. Gillman MW, Oakey H, Baghurst PA, Volkmer RE, Robinson JS, Crowther CA. Effect of treatment of gestational diabetes mellitus on obesity in the next generation. Diabetes Care. 2010;33(5):964–8. doi: 10.2337/dc09-1810. - DOI - PMC - PubMed
    1. Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med. 2005;352(24):2477–86. doi: 10.1056/NEJMoa042973. - DOI - PubMed

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