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. 2024 Oct 21;33(spe2):e20231162.
doi: 10.1590/S2237-96222024v33e20231162.en. eCollection 2024.

Hepatitis A vaccination coverage survey in 24-month-old children living in Brazilian capitals, 2020

[Article in English, Portuguese]
Winny Éveny Alves Moura  1 , Karlla Antonieta Amorim Caetano  1 , Juliana de Oliveira Roque E Lima  1 , Lays Rosa Campos  1 , Grazielle Rosa da Costa E Silva  1 , José Cássio de Moraes  2 , Ana Paula França  2 , Carla Magda Allan Santos Domingues  3 , Maria da Gloria Lima Cruz Teixeira  4 , Sheila Araújo Teles  1 ; ICV 2020 Group; Adriana Ilha da Silva  5 , Alberto Novaes Ramos Jr  6 , Ana Paula França  7 , Andrea de Nazaré Marvão Oliveira  8 , Antonio Fernando Boing  9 , Carla Magda Allan Santos Domingues  3 , Consuelo Silva de Oliveira  10 , Ethel Leonor Noia Maciel  5 , Ione Aquemi Guibu  11 , Isabelle Ribeiro Barbosa Mirabal, Jaqueline Caracas Barbosa, Jaqueline Costa Lima  12 , José Cássio de Moraes  7 , Karin Regina Luhm  13 , Karlla Antonieta Amorim Caetano  14 , Luisa Helena de Oliveira Lima  15 , Maria Bernadete de Cerqueira Antunes  16 , Maria da Gloria Teixeira  17 , Maria Denise de Castro Teixeira  18 , Maria Fernanda de Sousa Oliveira Borges  19 , Rejane Christine de Sousa Queiroz  20 , Ricardo Queiroz Gurgel  21 , Rita Barradas Barata  11 , Roberta Nogueira Calandrini de Azevedo  22 , Sandra Maria do Valle Leone de Oliveira  23 , Sheila Araújo Teles  14 , Silvana Granado Nogueira da Gama  24 , Sotero Serrate Mengue  25 , Taynãna César Simões  26 , Valdir Nascimento  27 , Wildo Navegantes de Araújo  28
Affiliations

Hepatitis A vaccination coverage survey in 24-month-old children living in Brazilian capitals, 2020

[Article in English, Portuguese]
Winny Éveny Alves Moura et al. Epidemiol Serv Saude. .

Abstract
in English, Spanish

Objective: To estimate hepatitis A vaccination coverage in 24-month-old children and identify factors associated with non-vaccination.

Methods: This was a survey involving a sample stratified by socioeconomic strata in capital cities (2020-2022), with coverage estimates and 95% confidence intervals (95%CI), the factor analysis was performed using the prevalence ratio (PR) by means of Poisson regression.

Results: Among 31,001 children, hepatitis A coverage was 88.1% (95%CI 86.8;89.2). Regarding socioeconomic strata (A/B), the variable immigrant parents/guardians was associated with non-vaccination (PR = 1.91; 95%CI 1.09;3.37); in strata C/D, children of Asian race/skin color (PR = 4.69; 95%CI 2.30;9.57), fourth-born child or later (PR = 1.68; 95%CI 1.06;2 .66), not attending daycare/nursery (PR = 1.67; 95%CI 1.24;2.24) and mother with paid work (PR = 1.42; 95%CI 1.16;1.74) were associated with non-vaccination.

Conclusion: Hepatitis A coverage was below the target (95%), suggesting that specificities of social strata should be taken into consideration.

Main results: Hepatitis A vaccination coverage was 88%. Non-vaccination was greater in children with immigrant guardians (strata A/B); of Asian race/skin color, fourth-born child or later, those not attending daycare/nursery and mother with paid work (C/D strata).

Implications for services: The results of this study contributed to the Ministry of Health and Health Departments in monitoring vaccination coverage and identifying factors that may negatively impact hepatitis A vaccination coverage.

Perspectives: Further research is needed on the impact of migration on hepatitis A vaccination and vaccination in general. Health managers should be attentive to the different factors affecting vaccination among social strata.

Objetivo: Estimar cobertura de vacunación contra hepatitis A en niños de 24 meses y identificar factores associados a falta de vacunación.

Métodos: Encuesta en muestra estratificada por estratos socioeconómicos en capitales (2020-2022), con estimación de cobertura e intervalos de confianza del 95% (IC95%) y análisis de factores por la razón de prevalencia (RP) mediante regresión de Poisson.

Resultados: En los 31.001 niños, la cobertura de hepatitis A fue del 88,1% (IC95% 86,8%; 89,2%). Em estratos socioeconómicos (A/B), variable padres/tutores inmigrantes se asoció con la ausência de vacunación (RP = 1,91; IC95% 1,09;3,37); en estratos C/D, variables niño amarillo (RP = 4,69; IC95% 2,30;9,57), cuarto orden de nacimiento o más (RP=1,68; IC95% 1,06;2,66), no asistir a guardería/jardín de infancia (RP = 1,67; IC95% 1,24;2,24) y madre con trabajo remunerado (RP = 1,42; IC95% 1,16;1,74) se asociaron la ausência de vacunación.

Conclusión: Cobertura de la hepatitis A por debajo del objetivo (95%), sugiriendo considerar las especificidades de los estratos sociales.

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Conflict of interest statement

CONFLICTS OF INTEREST: The authors declare they have no conflicts of interest.

Figures

Figure 1
Figure 1. Hepatitis A vaccination coverage in 24-month-old children (n = 31,001), living in capital cities, according to the region of Brazil, 2020-2021
Figure 2
Figure 2. Hepatitis A vaccination coverage in 24-month-old children (n = 31,001), living in capital cities, according to socioeconomic stratum, Brazil, 2020-202
Figura 1
Figura 1. Cobertura da vacina contra hepatite A em crianças com 24 meses de idade (n = 31.001), residentes nas capitais, de acordo com a região do Brasil, 2020-2021
Figura 2
Figura 2. Cobertura da vacina contra hepatite A em crianças com 24 meses de idade (n = 31.001), residentes nas capitais, segundo estrato socioeconômico, Brasil, 2020-2021
See this image and copyright information in PMC

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