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Case Reports
. 2024 Sep 23;16(9):e69967.
doi: 10.7759/cureus.69967. eCollection 2024 Sep.

Pleuropulmonary Epithelioid Hemangioendothelioma

Philippe Haroun  1   2 , Hanna Salame  3 , Denis Tack  3 , Romain Dehon  4
Affiliations
Case Reports

Pleuropulmonary Epithelioid Hemangioendothelioma

Philippe Haroun et al. Cureus. .

Abstract

We present the CT, thoracoscopic, and histological findings of a 55-year-old female with pleuropulmonary epithelioid hemangioendothelioma. The CT scan revealed pleuropulmonary lesions, and thoracoscopy allowed direct visualization and biopsy of the lesions. Histological analysis confirmed the diagnosis, emphasizing the utility of combining imaging, endoscopic, and pathological methods in diagnosing this rare tumor.

Keywords: ct chest; epitheloid hemangioendothelioma; pleural epithelioid hemangioendothelioma; pleuropulmonary; video-assisted-thoracoscopy.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Axial CT images showing complex and mildly spiculated pulmonary nodules (A, black arrows) presenting punctuate calcifications (B, white arrows) and a large left pleural effusion (B, *). Note fissural involvement of pulmonary nodules (C, black open arrow) and the presence of pleural tags (D, white open arrow)
CT: computed tomography
Figure 2
Figure 2. Coronal images of chest CT examinations at the carinal level at the time of current presentation to the emergency department (A) compared to a previous examination twenty years earlier (B)
CT: computed tomography
Figure 3
Figure 3. Intraoperative photo showing diffuse EHE nodular lesions within the parietal pleura (*)
EHE: epithelioid hemangioendothelioma
Figure 4
Figure 4. (A) Low-power examination of the pleural biopsy specimen, showing an ill-defined lesion (black circle). (B) High-power examination demonstrating fibrostromal reaction (white open arrow). Epithelioid cells (black open arrow) can also be visualized. (C) High-power examination showing cells exhibiting pleomorphism (black arrows). Note the presence of conglomerates of small abortive vascular structures (white arrows) manifesting with a pseudo-adipous aspect and wherein a red blood cell can be identified (*). (D) High-power examination showing a considerable amount of red blood cells (white circle) within the lumen of abortive vessels. Note the presence of dispersed hyaline globules (blue open arrows)
See this image and copyright information in PMC

References

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