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. 2024 Oct 24;8(11):e0552.
doi: 10.1097/HC9.0000000000000552. eCollection 2024 Nov 1.

A patient-centered approach to dietary supplements for patients with chronic liver disease

Jennifer C Lai  1 , Melinda Ring  2   3 , Anand Dhruva  4   5   6 , Gloria Y Yeh  7   8
Affiliations

A patient-centered approach to dietary supplements for patients with chronic liver disease

Jennifer C Lai et al. Hepatol Commun. .

Abstract

The use of dietary supplements by patients with chronic liver disease is prevalent and rising. Despite the known risks of dietary supplements, including hepatotoxicity, adulteration, and contamination, patients with chronic liver disease often turn to dietary supplements to support their liver and/or overall health but are not necessarily empowered with the information or guidance from their liver practitioner to do so. This article provides practitioners with a framework for balancing the risks and benefits of dietary supplements in patients with chronic liver disease, offering examples of independent resources and certifications to use this framework in clinical practice. We offer 3 common clinical scenarios to highlight how the use of this framework can improve communication and decision-making in clinical practice. By adapting principles from Integrative Medicine, this article advocates for a patient-centered approach to dietary supplements in patients with chronic liver disease, encouraging open dialogue between clinicians and their patients to facilitate informed decision-making and personalized care.

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Conflict of interest statement

Jennifer C. Lai consults and advises Novo Nordisk. She consults for GenFit, advises Boehringer Ingelheim, and received grants from Nestle Nutrition Institute. The remaining authors have no conflicts to report.

Figures

FIGURE 1
FIGURE 1
Conceptual framework for considering factors specific to the dietary supplement and the patient.
See this image and copyright information in PMC

References

    1. Hatch O. S.784—103rd Congress (1993–1994): Dietary Supplement Health and Education Act of 1994. 1994. Accessed January 2, 2024. https://www.congress.gov/bill/103rd-congress/senate-bill/784
    1. Mishra S, Stierman B, Gahche J, Potischman N. Dietary supplement use among adults: United States, 2017–2018. Natl Cent Health Stat Data Brief. 2021. https://www.cdc.gov/nchs/data/databriefs/db399-H.pdf - PubMed
    1. Fravel MA Ernst ME Gilmartin‐Thomas J Woods RL Orchard SG Owen AJ; ASPirin in Reducing Events in the Elderly Investigator Group . Dietary supplement and complementary and alternative medicine use among older adults in Australia and the United States. J Am Geriatr Soc. 2023;71:2219–2228. - PMC - PubMed
    1. Herbal and Dietary Supplements. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases; 2012. May 8, 2023. Accessed January 5, 2024. https://www.ncbi.nlm.nih.gov/books/
    1. Dietary and Herbal Supplements. National Center for Complementary and Integrative Health. Accessed January 23, 2024. https://www.nccih.nih.gov/health/dietary-and-herbal-supplements