Association of various symptoms and histological alterations in the diagnosis of pediatric ulcerative colitis

Abstract

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease (IBD) of the colon. Its presentation is varied, with the main symptoms being mucosanguineous diarrhea, abdominal pain, and weight loss. However, the diagnostic utility of these symptoms in pediatric populations is controversial. This study evaluates the clinicopathological association of different symptoms in UC through an analytical study of patients under 15 years of age who underwent upper and lower gastrointestinal endoscopy at a pediatric hospital between 2015 and 2022 for suspected IBD.