Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2024 Dec;30(6):e13306.
doi: 10.1111/ijn.13306. Epub 2024 Oct 24.

Prevalence and influencing factors of cognitive frailty among Chinese older adults: A systematic review and meta-analysis

Xie Lin  1   2 , Zhong Nian  1 , Liu Yang  3 , Zhang Qing  4 , Niu Zhenjun  2 , Heng Yanlin  5
Affiliations
Meta-Analysis

Prevalence and influencing factors of cognitive frailty among Chinese older adults: A systematic review and meta-analysis

Xie Lin et al. Int J Nurs Pract. 2024 Dec.

Abstract

Aims: Cognitive frailty refers to the coexistence of physical frailty and cognitive impairment in older adults, without a concurrent diagnosis of Alzheimer's disease or other dementias. This review aims to evaluate the prevalence of CF subtypes and identify influencing factors among Chinese older adults.

Methods: The following databases were searched: PubMed/Medline, Embase, Cochrane Library, WOS, PsycINFO and CNKI et al (1 January 2001 to 20 October 2022). The risk of bias was assessed using the Agency for Healthcare Research and Quality Evidence-based Practice Center Methods Guide. Stata 17.0 software was used to pool the prevalence of cognitive frailty, and the pooled odds ratio and 95% CI of the influencing factors were calculated.

Results: The meta-analysis (56 studies and 80,320 participants) revealed the following prevalence rates: CF (18.9%), reversible CF (19.5%), potentially reversible CF (17.5%), CF in community-dwelling older adults (14.3%), CF in nursing homes (22.7%) and CF in older inpatients (25.2%). Influential factors identified included age, gender, education, nutrition, depression, exercise, sleep and comorbidity.

Conclusions: The prevalence of CF among Chinese older adults is notably high, and it probably underestimates the prevalence of reversible cognitive frailty. It is crucial to encourage adherence to healthy behaviours, as it can effectively reduce and delay the onset of cognitive frailty.

Keywords: China; cognitive frailty; influencing factors; meta‐analysis; older adults; prevalence.

PubMed Disclaimer

References

REFERENCES

    1. Aprahamian, I., Suemoto, C. K., Aliberti, M., de Queiroz Fortes Filho, S., de Araújo Melo, J., Lin, S. M., & Filho, W. J. (2018). Frailty and cognitive status evaluation can better predict mortality in older adults? Archives of Gerontology and Geriatrics, 77, 51–56. https://doi.org/10.1016/j.archger.2018.04.005
    1. Bruscoli, M., & Lovestone, S. (2004). Is MCI really just early dementia? A systematic review of conversion studies. International Psychogeriatrics, 16(2), 129–140. https://doi.org/10.1017/S1041610204000092
    1. Bu, Z., Huang, A., Xue, M., Li, Q., Bai, Y., & Xu, G. (2021). Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta‐analysis. Brain and Behavior, 11(1), e01926. https://doi.org/10.1002/brb3.1926
    1. Cesari, M., Gambassi, G., Abellan van Kan, G., & Vellas, B. (2014). The frailty phenotype and the frailty index: Different instruments for different purposes. Age and Ageing, 43(1), 10–12. https://doi.org/10.1093/ageing/aft160
    1. Chang, J., Hou, W., Li, Y., Li, S., Zhao, K., Wang, Y., Hou, Y., & Sun, Q. (2022). Prevalence and associated factors of cognitive frailty in older patients with chronic kidney disease: A cross‐sectional study. BMC Geriatrics, 22(1), 681. https://doi.org/10.1186/s12877-022-03366-z

LinkOut - more resources