The mechanism of bacterial defense system DdmDE from Lactobacillus casei

Pingping Huang^#^{1

2}, Purui Yan^#^{1

2}, Lijie Guo^#^{1

2}, Wenying Fei^{1

2}, Zhaoxing Li^{1

2}, Jingxian Liu^{1

2}, Jianping Kong^{1

2}, Yue Yao^{1

2}, Meiling Lu^{2

3

4}, Yibei Xiao^{5

6

7

8}, Meirong Chen^{9

10

11}

Affiliations

¹ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
² State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China.
³ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China.
⁴ Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu, China.
⁵ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁶ State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁷ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China. yibei.xiao@cpu.edu.cn.
⁸ Engineering Research Center for Anti-infective Drug Discovery, Ministry of Education (ERCADD), Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁹ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China. chenmr@cpu.edu.cn.
¹⁰ State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China. chenmr@cpu.edu.cn.
¹¹ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China. chenmr@cpu.edu.cn.

^# Contributed equally.

PMID: 39448873
PMCID: PMC11614852 (available on 2025-12-01)
DOI: 10.1038/s41422-024-01042-y

The mechanism of bacterial defense system DdmDE from Lactobacillus casei

Pingping Huang et al. Cell Res. 2024 Dec.

. 2024 Dec;34(12):873-876.

doi: 10.1038/s41422-024-01042-y. Epub 2024 Oct 24.

Authors

Affiliations

¹ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
² State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China.
³ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China.
⁴ Department of Biochemistry, School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiangsu, China.
⁵ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁶ State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁷ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China. yibei.xiao@cpu.edu.cn.
⁸ Engineering Research Center for Anti-infective Drug Discovery, Ministry of Education (ERCADD), Nanjing, Jiangsu, China. yibei.xiao@cpu.edu.cn.
⁹ Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China. chenmr@cpu.edu.cn.
¹⁰ State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China. chenmr@cpu.edu.cn.
¹¹ Chongqing Innovation Institute of China Pharmaceutical University, Chongqing, China. chenmr@cpu.edu.cn.

^# Contributed equally.

PMID: 39448873
PMCID: PMC11614852 (available on 2025-12-01)
DOI: 10.1038/s41422-024-01042-y

No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: The authors declare no competing interests.

References

1. Koonin, E. V., Makarova, K. S. & Wolf, Y. I. Annu. Rev. Microbiol.71, 233–261 (2017). - PMC - PubMed
1. Doron, S. et al. Science359, eaar 4120 (2018).
1. Gao, L. et al. Science369, 1077–1084 (2020). - PMC - PubMed
1. Hampton, H. G., Watson, B. N. J. & Fineran, P. C. Nature577, 327–336 (2020). - PubMed
1. Georjon, H. & Bernheim, A. Nat. Rev. Microbiol.21, 686–700 (2023). - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

The mechanism of bacterial defense system DdmDE from Lactobacillus casei

Affiliations

The mechanism of bacterial defense system DdmDE from Lactobacillus casei

Authors

Affiliations

Conflict of interest statement

References

Publication types

Grants and funding

LinkOut - more resources

Full Text Sources