Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Sep 30;15(10):291.
doi: 10.3390/jfb15100291.

The Integration of Gold Nanoparticles into Dental Biomaterials as a Novel Approach for Clinical Advancement: A Narrative Review

Affiliations
Review

The Integration of Gold Nanoparticles into Dental Biomaterials as a Novel Approach for Clinical Advancement: A Narrative Review

Saharat Jongrungsomran et al. J Funct Biomater. .

Abstract

Gold nanoparticles (AuNPs) have gained significant attention in the biomedical field owing to their versatile properties. AuNPs can be customized by modifying their size, shape and surface characteristics. In recent years, extensive research has explored the integration of AuNPs into various dental materials, including titanium, polymethylmethacrylate (PMMA) and resin composites. This review aims to summarize the advancements in the application of modified AuNPs in dental materials and to assess their effects on related cellular processes in the dental field. Relevant articles published in English on AuNPs in association with dental materials were identified through a systematic search of the PubMed/MEDLINE, Embase, Scopus and ScienceDirect databases from January 2014 to April 2024. Future prospects for the utilization of AuNPs in the field of dentistry are surveyed.

Keywords: antimicrobial activity; cell adhesion; cell differentiation; cell proliferation; dental biomaterial; gold nanoparticles; osteogenic activity.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Flow diagram of search procedure.
Figure 2
Figure 2
AuNPs in biomedical fields.
Figure 3
Figure 3
AuNP-modified dental materials.

Similar articles

References

    1. AlKahtani R.N. The implications and applications of nanotechnology in dentistry: A review. Saudi Dent. J. 2018;30:107–116. doi: 10.1016/j.sdentj.2018.01.002. - DOI - PMC - PubMed
    1. Umapathy V.R., Natarajan P.M., SumathiJones C., Swamikannu B., Johnson W.M.S., Alagarsamy V., Milon A.R. Current trends and future perspectives on dental nanomaterials—An overview of nanotechnology strategies in dentistry. J. King Saud Univ.-Sci. 2022;34:102231. doi: 10.1016/j.jksus.2022.102231. - DOI
    1. Ko W.K., Heo D.N., Moon H.J., Lee S.J., Bae M.S., Lee J.B., Sun I.C., Jeon H.B., Kwon I.K., Park H.K. The Effect of Gold Nanoparticle Size on Osteogenic Differentiation of Adipose-derived Stem Cells. J. Colloid Interface Sci. 2015;438:68. doi: 10.1016/j.jcis.2014.08.058. - DOI - PubMed
    1. Li J., Li J.J., Zhang J., Wang X., Kawazoe N., Chen G. Gold nanoparticle size and shape influence on osteogenesis of mesenchymal stem cells. Nanoscale. 2016;8:7992–8007. doi: 10.1039/C5NR08808A. - DOI - PubMed
    1. Yuan L., Qi X., Qin G., Liu Q., Zhang F., Song Y., Deng J. Effects of Gold Nanostructures on Differentiation of Mesenchymal Stem Cells. Colloids Surf. B Biointerfaces. 2019;184:110494. doi: 10.1016/j.colsurfb.2019.110494. - DOI - PubMed

Grants and funding

LinkOut - more resources