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. 2024 Oct 25;24(1):1207.
doi: 10.1186/s12879-024-10098-5.

Magnitude of anemia and associated factors among HIV infected children on antiretroviral therapy in Awi zone health facilities, Northwest Ethiopia, 2023

Tameru Menberu  1 , Tewodros Getnet Amera  2 , Amanuel Addisu  3 , Molla Getie  1
Affiliations

Magnitude of anemia and associated factors among HIV infected children on antiretroviral therapy in Awi zone health facilities, Northwest Ethiopia, 2023

Tameru Menberu et al. BMC Infect Dis. .

Abstract

Background: Anemia is a common complication of HIV infected children and it is enabling HIV disease progression, and decreasing survival. In Ethiopia, there is limited evidence on the prevalence of anemia and its associated factors among HIV infected children particularly in the Awi Zone. Therefore, this study aimed to assess the magnitude and associated factors of anemia among HIV infected children on ART aged from 6 months to 15 year-old in ART Clinic, Awi-Zone, Ethiopia.

Objective: To assess the magnitude and associated factors of anemia among HIV infected children on antiretroviral therapy in Awi zone health facilities, Northwest, Ethiopia, 2022.

Methods: A facility based cross-sectional study design was conducted from October to December 2022. A simple random sampling method was used to select the study participants. Descriptive statistics, including frequencies and proportions was used to summarize the study variables and data had been entered in to Epi data 4.2 and exported to SPSS version 25. Bivariable logistic regression followed by multivariable logistic regression was performed. Degree of association between dependent and independent variables had been assessed using adjusted odds ratio with 95% CI at p value of ≤ 0.05.

Result: From 346 participants in the selected sample 339 (97.9%) of them responded. Prevalence of anemia was 13.3% (n = 45) among which, majority (44.4%) of them had mild anemia, while about (42.2%,) had moderate anemia and around 13.3%, of them were severely anemic. Baseline CD4 count (AOR = 6.58, 95% CI: 2.85-15.22), WHO clinical stage III or IV (AOR = 8.42, 95% CI = 3.47, 20.45), hookworm infection (AOR = 5.06, 95% CI = 2.04, 12) and malaria infection (AOR = 4.92, 95% CI (2.19-11.02) were significantly associated with anemia among children on HAART.

Conclusion: The prevalence of anemia among participants was relatively low in this study. However, a considerable proportion of participants had moderate to severe anemia. Lower CD4 count at enrolment, advanced HIV clinical stage, malaria and hookworm infection were significantly linked with anemia. Thus, it requires regular monitoring of anemia status in these patients for better clinical outcomes and quality of life improvements.

Keywords: Anemia; Awi zone; Children; Ethiopia; HIV.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Anemia classified as mild, moderate and severe among children who are on HAART in Awi zone health facilities, Northwest Ethiopia, 2023
Fig. 2
Fig. 2
Morphological feature of anemia among HIV infected children on HAART at Awi zone public health facilities, 2022
See this image and copyright information in PMC

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References

    1. World Health Organization. Health Topic. Anemia. Geneva: World Health Organization. 2016. https://www.who.int/health-topics/anaemia. Accessed September 11, 2021.
    1. Kassebaum NJ, Jasrasaria R, Naghavi M, et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014;123:615–24. - PMC - PubMed
    1. Global burden of diseases, Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018;392:1789–858. - PMC - PubMed
    1. God GP, Kasonka L, Susannah W, Rehman Andrea M, Molly Chisenga F, et al. Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy. BMC Med. 2015;13. 10.1186/s12916-015-0267-x. - PMC - PubMed
    1. Woodd Susannah GP, God M, Chisenga S, Joshua K, John R, Rehman et al. Effects on Anthropometry and Appetite of vitamins and minerals given in lipid nutritional supplements for malnourished HIV-Infected adults referred for antiretroviral therapy: results from the NUSTART Randomized Controlled Trial. J Acquir Immune Defic Syndrome, 2015. 68(4). - PMC - PubMed

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