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. 2024 Oct 25;24(1):331.
doi: 10.1186/s12893-024-02629-3.

Construction of a nomogram for preoperative deep vein thrombosis in pelvic fracture patients

Wencai Li #  1 , He Ling #  1 , Zhao Huang  1 , Yonghui Lao  1 , Junjie Liu  1 , Gaoyong Deng  1 , Wei Su  1 , Rongbin Lu  2
Affiliations

Construction of a nomogram for preoperative deep vein thrombosis in pelvic fracture patients

Wencai Li et al. BMC Surg. .

Abstract

Background: In recent years, the incidence of pelvic fractures has been on the rise, predominantly affecting the elderly population. Deep vein thrombosis may lead to poor prognosis in patients. monocyte-to-lymphocyte ratio is novel biomarkers of inflammation, and this study aims to verify their predictive effect and construct the nomogram model.

Method: This study used binary logistic regression analysis to predict the predictive effect of MLR on the occurrence of DVT in pelvic fractures patients. And use R studio to construct nomogram model.

Result: The results showed that Age (1.04 [1.01, 1.07], p = 0.006), WBC (1.44 [1.28, 1.61], p < 0.001), and MLR (2.11 [1.08, 4.13], p = 0.029) were independent predictive factors. The nomogram demonstrated good predictive performance with small errors in both the training and validation groups, and most clinical patients could benefit from them.

Conclusion: The nomogram constructed based on MLR can assist clinicians in early assessment of the probability of DVT occurrence.

Keywords: Deep vein thrombosis; Monocyte to lymphocyte ratio; Nomogram; Pelvic fractures.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Flow chart of this study
Fig. 2
Fig. 2
Box plot of clinical differential factors
Fig. 3
Fig. 3
Receiver operating characteristic of clinical differential factors
Fig. 4
Fig. 4
The nomogram of the study
Fig. 5
Fig. 5
Receiver operating characteristic of nomogram. A. Training test; B. Validation test
Fig. 6
Fig. 6
Calibration plot of the nomogram. A. Training test; B. Validation test
Fig. 7
Fig. 7
DCA curve of the nomogram. A. Training test; B. Validation test
See this image and copyright information in PMC

References

    1. Khalifa AA, Mahran DG, Fergany A, Farouk O. Epidemiology of acetabular fractures in elderly patients and the effect of various management options on the outcomes. A comprehensive narrative review. Int J Orthop Trauma Nurs. 2024;101049. 10.1016/j.ijotn.2023.101049 - PubMed
    1. Moore D, Gnap R, Monsell F. Traumatic injuries of the immature hip and pelvis. Curr OpinPediatr. 2024;36(1):90-7. 10.1097/MOP.0000000000001301 - PubMed
    1. Warner Stephen J, Haase Douglas R, Chip Routt Milton L, Eastman Jonathan G, Achor Timothy S. Use of 3D fluoroscopy to assist in the reduction and fixation of pelvic and Acetabular fractures: a Safety and Quality Case Series. J Orthop Trauma. 2023;37(null):S1–6. 10.1097/BOT.0000000000002686. - PubMed
    1. Wier Julian, Reza F, Andrew D, Patterson Joseph T. Underweight patients experience higher inpatient complication and mortality rates following acetabular fracture. Eur J Orthop Surg Traumatol. 2023. 10.1007/s00590-023-03739-z. - PMC - PubMed
    1. Hsiao P-M, Chen LS-C, Yu Yi-Hsun. Incidence of deep vein thrombosis and symptomatic pulmonary embolism in Taiwanese patients with pelvic and/or acetabular fractures: a retrospective study. Sci Rep. 2023;13(1):16352. 10.1038/s41598-023-43449-4. - PMC - PubMed

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