Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Practice Guideline
. 2024 Dec;129(12):1778-1789.
doi: 10.1007/s11547-024-01900-0. Epub 2024 Oct 26.

Italian guidelines for age range and test interval in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines

Silvia Deandrea  1   2 , Paola Mantellini  3 , Paolo Giorgi Rossi  4 , Riccardo Vecchio  5 , Matteo Capobussi  6 , Marco Rosselli Del Turco  7 , Francesca Pietribiasi  8 , Lauro Bucchi  9 , Carlo Senore  10 , Francesco Sardanelli  11 , Francesca Battisti  12 , Livia Giordano  10 , Eugenio Paci  7 , Elena Parmelli  13   14 , Gianni Saguatti  15 , Marco Zappa  7 ; Italian mammography screening, diagnosis guidelines Technical/Scientific Committee, Panel, Reviewers
Collaborators, Affiliations
Practice Guideline

Italian guidelines for age range and test interval in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines

Silvia Deandrea et al. Radiol Med. 2024 Dec.

Abstract

A guideline panel formulated a set of recommendations for breast cancer screening and diagnosis to implement clinical activities in Italy in alignment with the European Breast Cancer Guidelines on Screening and Diagnosis (European Commission Initiative on Breast Cancer-ECIBC). The panel issued national recommendations through adopting, adapting, and/or developing recommendations from the European guidelines (ADOLOPMENT approach). This process utilizes the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence to decision (EtD) framework. An additional PubMed search was conducted using search terms specific to Italy to tailor the EU guidelines to the national context. Nine articles were included as contextual evidence in the EtD. A total of 13 recommendations were finalized, either adapted or adopted to suit the national context. Organized breast cancer screening is strongly recommended for women aged 50-69 every 2 years, and it is conditionally recommended every 3 years for women aged 70-74, as well as every 1 or 2 years for women aged 45-49. Annual mammography received a strong recommendation against for women aged 50 and older. Developing shared national guidelines for the management of mammography screening will improve the standardization of processes across all settings, thereby promoting health equity.

Keywords: ADOLOPMENT; Breast neoplasms; Europe; GRADE approach; Italy; Mass screening.

PubMed Disclaimer

Conflict of interest statement

Declarations. Conflict of interest: Silvia Deandrea is the President of the Italian Mammography Screening Group; Marco Rosselli Del Turco was a medical consultant for senology at FORA s.p.a. Paolo Giorgi Rossi is a member of the panel that developed the European guidelines on breast cancer screening and diagnosis, referred document for the ADOLOPMENT process; Livia Giordano is a member of the panel that developed the European guidelines on breast cancer screening and diagnosis, referred document for the ADOLOPMENT process; Elena Parmelli was a contract staff member at the Joint Research Centre (JRC) of the European Commission, Ispra, VA (Italy); Cannatà Vittorio has been Vice-President of the Italian Association of Medical Physics (AIFM); Isabella Castellano has been professional consultant for symposium “Choosing the best therapy in ER + /HER2- breast cancer” (Token of attendance at the National Congress of Anatomic Pathology, October 2019), Myriad Genetics, s.r.l.; Stefano Pacifici is the President of the Italian Association of Senology Radiographers (AITeRS); Trianni Annalisa is a member of the Italian Association of Medical Physics (AIFM); Paola Golinelli was reimbursed for participation in the European Federation of Organization for Medical Physics (EFOMP) Working Group on mammographic tomosynthesis equipment. Pierpaolo Pattacini received a software by I-CAD. The other authors have no relevant financial or non-financial interest to disclose. Competing interests: All panellists were required to disclose all financial, non-financial, personal, and institutional interests relevant to the scope of the guidelines by completing a standardized form, following SNLG guidance. The Scientific Committee (SC) assessed each individual interest, and ultimately, no panellist was excluded from the voting procedures. This policy was upheld throughout the entire process, including the selection of panel members, the generation and prioritization of research questions, and participation in the formulation of recommendations. The SC consistently monitored the declaration of conflicts of interest (COI). Ethical approval: Ethical approval was not necessary for this kind of scientific work. Informed consent: Not applicable.

References

    1. Bray F, Laversanne M, Sung H et al (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. https://doi.org/10.3322/caac.21834 - DOI - PubMed
    1. ECIS—European Cancer Information System: European Commission. https://ecis.jrc.ec.europa.eu/ . Accessed September 1, 2019
    1. Independent UK Panel on Breast Cancer Screening (2012) The benefits and harms of breast cancer screening: an independent review. Lancet (London, England) 380(9855):1778–1786. https://doi.org/10.1016/S0140-6736(12)61611-0 - DOI
    1. Ponti, A., Anttila, A., Ronco, G., et al. (2017). Cancer Screening in the European Union: Report on the implementation of the Council Recommendation on cancer screening. International Agency for Research on Cancer. https://health.ec.europa.eu/system/files/2017-05/2017_cancerscreening_2n... . Accessed January 25, 2024.
    1. Battisti F, Mantellini P, Falini P et al (2022) Key performance indicators of breast cancer screening programmes in Italy, 2011–2019. Annali dell’Istituto superiore di sanita 58(4):244–253. https://doi.org/10.4415/ANN_22_04_04 - DOI - PubMed

Publication types

LinkOut - more resources