Declaration of Competing Interests INTERLACE was funded by Cancer Research UK and supported by the UCL clinical trials unit. RTTQA is funded by NIHR. GE reports consulting fees from MSD and Eisai; honoraria from Eisai and GSK; advisory board for MSD and GSK, and travel expenses from MSD. PD has no conflicts to report. MM reports consulting fees from Eisai and GSK; honoraria from Eisai, GSK, MSD, Roche, ASCO; travel expenses from Roche; member of CCRN/GCIG/ASCO international affairs committee.