Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Dec;34(12):4452-4458.
doi: 10.1007/s11695-024-07557-y. Epub 2024 Oct 26.

Eight Year Follow-Up After Gastric Bypass and Sleeve Gastrectomy in a Brazilian Cohort: Weight Trajectory and Health Outcomes

Marianna Lins de Souza Salerno  1   2 , Carolina Garcia Soares Leães Rech  3   4 , Pedro Bortoluzzi Escobar da Silva  4 , Antonio Carlos Weston  3 , Luis Alberto de Carli  3 , Julia Fernanda Pereira-Lima  5   4
Affiliations

Eight Year Follow-Up After Gastric Bypass and Sleeve Gastrectomy in a Brazilian Cohort: Weight Trajectory and Health Outcomes

Marianna Lins de Souza Salerno et al. Obes Surg. 2024 Dec.

Abstract

Introduction: Despite Sleeve Gastrectomy (SG) being the most commonly performed bariatric surgery today, studies with over 5 years of follow-up show that patients undergoing SG have inferior weight loss compared to those undergoing Roux-en-Y gastric bypass (RYGB). The aim of this study was to examine differences in weight loss and the prevalence of weight regain between SG and RYGB up to 8 years after surgery.

Methods: Retrospective study including adult patients undergoing SG or RYGB between 2015 and 2018 at a tertiary center in Brazil. We evaluate the weight trajectory and pre- and postoperative behavior of type 2 diabetes (T2D), hypertension, and dyslipidemia. Differences betwen variables were tested using Student t-test, Mann-Whitney U, Pearson's chi-square or Fisher's exact test as appropriate. The level of significance adopted was p < 0,005.

Results: Among 591 patients (40 ± 10 years; baseline body mass index 41.7 [IQR 39.1-45]; 83% women), 327 underwent RYGB (55%) and 264 SG (45%). Preoperatively, 14% had T2D, 40% hypertension, and 53% dyslipidemia. The mean total percentage of weight loss was higher in the RYGB group after 8 years: 32% compared to 19% after SG (difference 13%, p < 0.004). At 8 years, weight regain was also lower in RYGB (23%) compared to SG (39%) (p < 0.001). At 5 years postoperatively, the remission rates for T2D, hypertension, and dyslipidemia were 63%, 42%, and 51%, respectively, among the patients who remained in follow-up.

Conclusions: Patients undergoing RYGB showed greater weight loss and less weight regain 8 years after bariatric surgery compared to those undergoing SG.

Keywords: Bariatric surgery; Long-term outcomes; Roux-en-Y gastric bypass; Sleeve gastrectomy; Weight regain.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethical Approval: The study was approved by the Research Ethics Committee (n° 6005804). For this type of study formal consent is not required. Informed Consent: Informed consent does not apply. Conflict of Interest: The authors declare no conflict of interest.

References

    1. World Obesity Federation. World Obesity Atlas 2023. Available from: https://data.worldobesity.org/publications/?cat=19 . Accessed 20 Mar 2024
    1. World Health Organization [WHO]. Obesity and overweight. 2024. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight . Accessed 2 Apr 2024
    1. Bhaskaran K, Dos-Santos-Silva I, Leon DA, Douglas IJ, Smeeth L. Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK. Lancet Diabetes Endocrinol. 2018;6(12):944–53. - DOI - PubMed - PMC
    1. Sjöström L, Narbro K, Sjöström CD, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52. - DOI - PubMed
    1. O’Brien PE, Hindle A, Brennan L, et al. Long-term outcomes after bariatric surgery: A systematic review and meta-analysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding. Obes Surg. 2019;29(1):3–14. - DOI - PubMed