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Comment
. 2024 Nov 5;121(45):e2419368121.
doi: 10.1073/pnas.2419368121. Epub 2024 Oct 28.

Gut Microbes Participate in Host Polyamine Metabolism

Affiliations
Comment

Gut Microbes Participate in Host Polyamine Metabolism

Leilei Yu et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Competing interests statement:The authors declare no competing interest.

Figures

Fig. 1.
Fig. 1.
Gut-microbe-derived small RNAs reduce polyamine levels in the host colon by inhibiting the expression of genes related to polyamine-metabolizing enzymes. (A) Discovery of key gut microbiota species influencing host polyamine metabolism. (B) Identification of critical bioactive components in Lactobacillus murinus involved in regulating host polyamine metabolism. (C) Investigation of the relationship between small RNAs of L. murinus and the pathogenesis of colitis and colorectal cancer. (D) Summary diagram showing L. murinus-derived small RNAs participating in host polyamine metabolism.

Comment on

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