Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jan 30;2(2):62-64.
doi: 10.1021/envhealth.4c00002. eCollection 2024 Feb 16.

Modulating GSK3β Phosphorylation: Bio-Corona Protective Effects Against Silica Nanoparticle-Induced Neurotoxicity

Affiliations

Modulating GSK3β Phosphorylation: Bio-Corona Protective Effects Against Silica Nanoparticle-Induced Neurotoxicity

Xin Qiao et al. Environ Health (Wash). .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Route-dependent corona formation determined GSK3β phosphorylation status and ultimately the toxic behavior of SiO2 NPs. Reproduced from ref (13). Copyright 2023 The Authors.

Similar articles

References

    1. Poon W.; Kingston B. R.; Ouyang B.; Ngo W.; Chan W. C. W. A framework for designing delivery systems. Nat. Nanotechnol. 2020, 15 (10), 819–829. 10.1038/s41565-020-0759-5. - DOI - PubMed
    1. Corbo C.; Molinaro R.; Parodi A.; Toledano Furman N. E.; Salvatore F.; Tasciotti E. The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery. Nanomedicine 2016, 11 (1), 81–100. 10.2217/nnm.15.188. - DOI - PMC - PubMed
    1. Wheeler K. E.; Chetwynd A. J.; Fahy K. M.; Hong B. S.; Tochihuitl J. A.; Foster L. A.; Lynch I. Environmental dimensions of the protein corona. Nat. Nanotechnol. 2021, 16 (6), 617–629. 10.1038/s41565-021-00924-1. - DOI - PubMed
    1. Cai R.; Ren J.; Guo M.; Wei T.; Liu Y.; Xie C.; Zhang P.; Guo Z.; Chetwynd A. J.; Ke P. C.; Lynch I.; Chen C. Dynamic intracellular exchange of nanomaterials’ protein corona perturbs proteostasis and remodels cell metabolism. Proc. Natl. Acad. Sci. U.S.A. 2022, 119 (23), e220036311910.1073/pnas.2200363119. - DOI - PMC - PubMed
    1. Ren J.; Cai R.; Wang J.; Daniyal M.; Baimanov D.; Liu Y.; Yin D.; Liu Y.; Miao Q.; Zhao Y.; Chen C. Precision nanomedicine development based on specific opsonization of human cancer patient-personalized protein coronas. Nano Lett. 2019, 19 (7), 4692–4701. 10.1021/acs.nanolett.9b01774. - DOI - PubMed

LinkOut - more resources