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Clinical Trial
. 1986 Jan;80(1):50-4.
doi: 10.1016/0007-0971(86)90009-4.

Is driving gas flow rate clinically important for nebulizer therapy?

J W Hadfield, W J Windebank, J R Bateman
Clinical Trial

Is driving gas flow rate clinically important for nebulizer therapy?

J W Hadfield et al. Br J Dis Chest. 1986 Jan.

Abstract

Ten patients with stable asthma were studied to see whether the flow rate used to drive a nebulizer was clinically important. Each received 1 mg of salbutamol in 2 ml of physiological saline via a Sandoz 'Lifeline' nebulizer driven by piped oxygen at 8, 6 and 4 litres/min on separate randomly allocated occasions. Although the time for nebulization was significantly longer as flow rate was reduced, there was no significant difference in the bronchodilator response.

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