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Meta-Analysis
. 2024 Oct 25:39:e397224.
doi: 10.1590/acb397224. eCollection 2024.

Robotic surgery versus conventional laparoscopy in colon cancer patients: a systematic review and meta-analysis

Giuliana Fulco Gonçalves  1   2 , Pedro Vilar de Oliveira Villarim  1   3 , Vitória Ribeiro Dantas Marinho  1   2 , Clarissa Amaral Abreu  1   2 , Luiz Henrique Moreira Pereira  1   3 , Luiz Henrique Moreira Pereira  1   3 , Sofia Emerenciano Gurgel  1 , Amália Cínthia Meneses Rêgo  1   2   4 , Kleyton Santos de Medeiros  1   4   5 , Irami Araújo-Filho  1   2   3   4
Affiliations
Meta-Analysis

Robotic surgery versus conventional laparoscopy in colon cancer patients: a systematic review and meta-analysis

Giuliana Fulco Gonçalves et al. Acta Cir Bras. .

Abstract

Purpose: To compare robotic versus laparoscopic colectomies in colon cancer patients in general complications.

Methods: Nine databases were searched for randomized controlled trials (RCT) investigating patients with colon cancer, submitted to robotic surgery (RS) compared to a laparoscopic (LC) approach. The risk of bias was assessed using RoB 2.0 tool, and certainty of the evidence was evaluated by Grading of Recommendations, Assessment, Development and Evaluation (GRADE). Data synthesis was performed using the software R. The meta-analysis of the included studies was carried out using the fixed-effects model (DerSimonian and Laird). Heterogeneity was measured using I2 analysis.

Results: A total of four studies were used with 293 patients. Three studies were used in this comparative LC vs. RS when evaluating infection rates on surgical wound sites. The odds ratio (OR) appeared to be slightly favorable to LC (OR = 3.05; 95% confidence interval-95%CI 0.78-11.96). In the hospitalization rates analysis, two randomized controlled trials were used, and the mean differences slightly favored the RS (MD = -0.54; 95%CI -2.28-1.19). GRADE evaluation detected a serious risk of bias due to RCT format and RoB-2 concurred.

Conclusion: Both types of procedures seem to have their own benefits, risks, and limitations. They seem close to equal in terms of postsurgical infection and hospitalization.

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Conflict of interest statement

Conflict of interest: Nothing to declare.

Figures

Figure 1
Figure 1. Flowchart for study selection. PRISMA flow diagram for systematic review and meta-analysis.
Figure 2
Figure 2. Forest plot for surgical infection rates.
Figure 3
Figure 3. Forest plot for mean length of hospital stay.
See this image and copyright information in PMC

References

    1. van Rooijen S, Carli F, Dalton S, Thomas G, Bojesen R, Le Guen M, Barizien N, Awasthi R, Minnella E, Beijer S, Martínez-Palli G, van Lieshout R, Gögenur I, Feo C, Johansen C, Scheede-Bergdahl C, Roumen R, Schep G, Slooter G. Multimodal prehabilitation in colorectal cancer patients to improve functional capacity and reduce postoperative complications: the first international randomized controlled trial for multimodal prehabilitation. BMC Cancer. 2019;19(1):98–98. doi: 10.1186/s12885-018-5232-6. - DOI - PMC - PubMed
    1. Trastulli S, Cirocchi R, Desiderio J, Coratti A, Guarino S, Renzi C, Corsi A, Boselli C, Santoro A, Minelli L, Parisi A. Robotic versus laparoscopic approach in colonic resections for cancer and benign diseases: systematic review and meta-analysis. PLoS One. 2015;10(7):e0134062. doi: 10.1371/journal.pone.0134062. - DOI - PMC - PubMed
    1. Abu Gazala M, Wexner SD. Re-appraisal and consideration of minimally invasive surgery in colorectal cancer. Gastroenterol Rep (Oxf) 2017;5(1):1–10. doi: 10.1093/gastro/gox001. - DOI - PMC - PubMed
    1. Roh HF, Nam SH, Kim JM. Robot-assisted laparoscopic surgery versus conventional laparoscopic surgery in randomized controlled trials: A systematic review and meta-analysis. PLoS One. 2018;13(1):e0191628. doi: 10.1371/journal.pone.0191628. - DOI - PMC - PubMed
    1. Leal Ghezzi T, Campos Corleta O. 30 years of robotic surgery. World J Surg. 2016;40(10):2550–2557. doi: 10.1007/s00268-016-3543-9. - DOI - PubMed

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