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Review
. 2024 Dec:82:102652.
doi: 10.1016/j.pbi.2024.102652. Epub 2024 Oct 30.

Unlocking diversity from wild relatives of perennial fruit crops in the pan-genomics era

Jean Sabety  1 , Anze Svara  1 , Richard Tegtmeier  1 , Hana Feulner  1 , Patrick Cho  1 , Aafreen Sakina  1 , David Hickok  1 , Awais Khan  2
Affiliations
Review

Unlocking diversity from wild relatives of perennial fruit crops in the pan-genomics era

Jean Sabety et al. Curr Opin Plant Biol. 2024 Dec.

Abstract

Crop wild relatives of perennial fruit crops have a wealth of untapped genetic diversity that can be utilized for cultivar development. However, barriers such as linkage drag, long juvenility, and high heterozygosity have hindered their utilization. Advancements in genome sequencing technologies and assembly methods, combined with the integration of chromosome conformation capture have made it possible to construct high-quality reference genomes. These genome assemblies can be combined into pan-genomes, capturing inter- and intraspecific variations across coding and non-coding regions. Pan-genomes of perennial fruit crops are being developed to identify the genetic basis of traits. This will help overcome breeding challenges, enabling faster and more targeted development of new cultivars with novel traits through breeding and biotechnology.

Keywords: Domestication; Pan-genome; Perennials; Undomesticated.

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Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Awais Khan reports financial support was provided by USDA National Institute of Food and Agriculture (NIFA) Agriculture - Food Research Initiative (AFRI). Awais Khan reports financial support was provided by New York State Department of Agriculture & Markets, Apple Research & Development Program (ARDP). If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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