Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov-Dec;38(6):2820-2826.
doi: 10.21873/invivo.13762.

Oncological and Surgical Outcomes of Oncoplastic Reduction Mammoplasty: A Single-centre Retrospective Study

Jérôme Martineau  1 , Boran Tekdogan  1 , Giang-Thanh Lam  2 , Daniel Correia  1 , Salvatore Giordano  3 , Daniel F Kalbermatten  1 , Carlo M Oranges  4
Affiliations

Oncological and Surgical Outcomes of Oncoplastic Reduction Mammoplasty: A Single-centre Retrospective Study

Jérôme Martineau et al. In Vivo. 2024 Nov-Dec.

Abstract

Background/aim: Breast-conserving surgery is the preferred treatment for early-stage breast cancer but can often result in unsatisfactory cosmetic outcomes. Oncoplastic surgery aims to improve both oncologic and aesthetic outcomes by combining local excision with plastic surgery techniques. Using breast reduction techniques in breast cancer treatment has been shown to allow for wider margins of excision, leading to enhanced oncological safety and reduced recurrence rates without causing significant asymmetry. This study aimed to analyze the surgical and oncological outcomes of a large cohort of patients undergoing oncoplastic reduction mammoplasty (ORM).

Patients and methods: A retrospective analysis of postoperative surgical and oncological outcomes of all patients who underwent ORM at a single center between January 2018 and December 2023 was performed. Preoperative patient characteristics, operative and post-operative outcomes were recorded and analyzed.

Results: A total of 67 patients that underwent oncologic breast reduction were included in the final analysis - representing a total of 71 ORM, with a mean (SD) age of 53.1 (10.5) years and a mean (SD) BMI of 28.8 (5.9) kg/m2 A superomedial pedicle-based technique was the most frequently used (36.6%), followed by inferior pedicle-based technique (28.1%). A complication rate of 18.3% on the ipsilateral side was observed. Salvage surgery was necessary in five cases (7.0%) due to positive margins - with one patient (1.4%) requiring margin expansion surgery and four (5.6%) a completion mastectomy.

Conclusion: This monocentric retrospective study shows that ORM is safe, with a complication rate on par with conventional breast reduction and offers satisfactory oncological outcomes.

Keywords: Oncoplastic mammoplasty; breast; breast cancer; breast reduction; cohort study; reconstruction.

PubMed Disclaimer

Conflict of interest statement

The Authors have no conflicts of interest to declare in relation to this study.

Figures

Figure 1
Figure 1
Preoperative views of a 53-year-old patient presenting with the diagnosis of invasive ductal carcinoma of the upper inner quadrant of the left breast and an important asymmetry in favor of the right breast, lateral (A, E), frontal (C) and semi-lateral (B, D). The indication for oncoplastic reduction mammoplasty on the left breast and immediate symmetrization of the right breast is posed after multidisciplinary tumor board discussion.
Figure 2
Figure 2
Preoperative drawings, based on a keyhole wise pattern. A breast marking harpoon was placed under ultrasound control preoperatively in the left-breast to guide tumor resection.
Figure 3
Figure 3
Postoperative result - lateral (A, E), frontal (C) and semi-lateral (B, D) views at 12 months, following an oncoplastic reduction mammoplasty of the left breast and an immediate symmetrization of the contralateral breast, using an inferior pedicle technique on both sides. The weight of the resected tumor was 35 g and the reduction weight on the right side was 181 g.
See this image and copyright information in PMC

References

    1. Veronesi U, Cascinelli N, Mariani L, Greco M, Saccozzi R, Luini A, Aguilar M, Marubini E. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347(16):1227–1232. doi: 10.1056/NEJMoa020989. - DOI - PubMed
    1. Fisher B, Anderson S, Bryant J, Margolese RG, Deutsch M, Fisher ER, Jeong JH, Wolmark N. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347(16):1233–1241. doi: 10.1056/NEJMoa022152. - DOI - PubMed
    1. Cochrane RA, Valasiadou P, Wilson ARM, Al-Ghazal SK, Macmillan RD. Cosmesis and satisfaction after breast-conserving surgery correlates with the percentage of breast volume excised. Br J Surg. 2003;90(12):1505–1509. doi: 10.1002/bjs.4344. - DOI - PubMed
    1. Waljee JF, Hu ES, Ubel PA, Smith DM, Newman LA, Alderman AK. Effect of esthetic outcome after breast-conserving surgery on psychosocial functioning and quality of life. J Clin Oncol. 2008;26(20):3331–3337. doi: 10.1200/JCO.2007.13.1375. - DOI - PubMed
    1. Kosasih S, Tayeh S, Mokbel K, Kasem A. Is oncoplastic breast conserving surgery oncologically safe? A meta-analysis of 18,103 patients. Am J Surg. 2020;220(2):385–392. doi: 10.1016/j.amjsurg.2019.12.019. - DOI - PubMed

LinkOut - more resources