Recognition and management of a malignant hyperthermia crisis: updated 2024 guideline from the European Malignant Hyperthermia Group

Klaus P E Glahn¹, Thierry Girard², Anna Hellblom³, Philip M Hopkins⁴, Stephan Johannsen⁵, Henrik Rüffert⁶, Marc M Snoeck⁷, Albert Urwyler²; European Malignant Hyperthermia Group

Collaborators, Affiliations

Collaborators

European Malignant Hyperthermia Group:
O Bandschapp⁸, B Bastian⁹, D Bendixen¹, J Bilmen¹⁰, J C Brand¹¹, T Bulger¹², A-F Dalmas¹³, O Diaz-Cambronero¹⁴, R Gillies¹⁵, V Glauber¹⁶, L Heytens¹⁷, A Michalek-Sauberer¹⁸, H C A Silva¹⁹, D Štěpánková²⁰, V Tegazzin²¹

Affiliations

¹ Danish Malignant Hyperthermia Centre, Department of Anaesthesia, Herlev University Hospital, Copenhagen, Denmark.
² Department of Anaesthesiology, University Hospital Basel and University of Basel, Basel, Switzerland.
³ Department of Anaesthesia, University Hospital, Lund, Sweden.
⁴ Malignant Hyperthermia Unit, St James's University Hospital, Leeds, UK. Electronic address: p.m.hopkins@leeds.ac.uk.
⁵ Department of Anaesthesia and Critical Care, University of Wuerzburg, Wuerzburg, Germany.
⁶ Helios Klinik Schkeuditz, Klinik für Anästhesie, Intensivmedizin, Schmerztherapie, Leipzig-Schkeuditz, Germany; MH Center University Hospital Leipzig, Department of Anaesthesiology and Intensive Care Medicine, Leipzig, Germany.
⁷ Department of Anaesthesiology, Canisius-Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
⁸ Universitätsspital, Basel, Switzerland.
⁹ Department of Anaesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany.
¹⁰ Malignant Hyperthermia Unit, St James's University Hospital, Leeds, UK.
¹¹ Malignant Hyperthermia Unit, Midstream Mediclinic Hospital, Pretoria, South Africa.
¹² Palmerston North Hospital, Palmerston North, New Zealand.
¹³ Clinique d'Anesthésie-Réanimation, Hôpital Jeanne de Flandre, Lille, France.
¹⁴ Department Anesthesiology, Perioperative Medicine Research Unit, Hospital Universitari i Politécnic la Fe, Valencia, Spain.
¹⁵ Royal Melbourne Hospital, Melbourne, VIC, Australia.
¹⁶ The Chaim Sheba Medical Center, Department of Anesthesiology and Intensive Care Unit, Sackler School of Medicine, Tel Aviv University, Israel.
¹⁷ Universitair Ziekenhuis, Antwerp, Belgium.
¹⁸ Klinik für Anästhesie und allgemeine Intensivmedizin der Universität Wien, Vienna, Austria.
¹⁹ Malignant Hyperthermia Centre, Discipline of Anaesthesia, Pain, and Intensive Care, Universidade Federal de São Paulo, São Paulo, Brazil.
²⁰ MH Unit, Department of Children's Anaesthesiology and PICU, University Hospital Brno, Czech Republic.
²¹ San Antonio General Hospital, Padua, Italy.

PMID: 39482150
DOI: 10.1016/j.bja.2024.09.022

Recognition and management of a malignant hyperthermia crisis: updated 2024 guideline from the European Malignant Hyperthermia Group

Klaus P E Glahn et al. Br J Anaesth. 2025 Jan.

. 2025 Jan;134(1):221-223.

doi: 10.1016/j.bja.2024.09.022. Epub 2024 Oct 30.

Authors

Klaus P E Glahn¹, Thierry Girard², Anna Hellblom³, Philip M Hopkins⁴, Stephan Johannsen⁵, Henrik Rüffert⁶, Marc M Snoeck⁷, Albert Urwyler²; European Malignant Hyperthermia Group

Collaborators

European Malignant Hyperthermia Group:
O Bandschapp⁸, B Bastian⁹, D Bendixen¹, J Bilmen¹⁰, J C Brand¹¹, T Bulger¹², A-F Dalmas¹³, O Diaz-Cambronero¹⁴, R Gillies¹⁵, V Glauber¹⁶, L Heytens¹⁷, A Michalek-Sauberer¹⁸, H C A Silva¹⁹, D Štěpánková²⁰, V Tegazzin²¹

Affiliations

¹ Danish Malignant Hyperthermia Centre, Department of Anaesthesia, Herlev University Hospital, Copenhagen, Denmark.
² Department of Anaesthesiology, University Hospital Basel and University of Basel, Basel, Switzerland.
³ Department of Anaesthesia, University Hospital, Lund, Sweden.
⁴ Malignant Hyperthermia Unit, St James's University Hospital, Leeds, UK. Electronic address: p.m.hopkins@leeds.ac.uk.
⁵ Department of Anaesthesia and Critical Care, University of Wuerzburg, Wuerzburg, Germany.
⁶ Helios Klinik Schkeuditz, Klinik für Anästhesie, Intensivmedizin, Schmerztherapie, Leipzig-Schkeuditz, Germany; MH Center University Hospital Leipzig, Department of Anaesthesiology and Intensive Care Medicine, Leipzig, Germany.
⁷ Department of Anaesthesiology, Canisius-Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
⁸ Universitätsspital, Basel, Switzerland.
⁹ Department of Anaesthesiology and Intensive Care Medicine, University Hospital Leipzig, Leipzig, Germany.
¹⁰ Malignant Hyperthermia Unit, St James's University Hospital, Leeds, UK.
¹¹ Malignant Hyperthermia Unit, Midstream Mediclinic Hospital, Pretoria, South Africa.
¹² Palmerston North Hospital, Palmerston North, New Zealand.
¹³ Clinique d'Anesthésie-Réanimation, Hôpital Jeanne de Flandre, Lille, France.
¹⁴ Department Anesthesiology, Perioperative Medicine Research Unit, Hospital Universitari i Politécnic la Fe, Valencia, Spain.
¹⁵ Royal Melbourne Hospital, Melbourne, VIC, Australia.
¹⁶ The Chaim Sheba Medical Center, Department of Anesthesiology and Intensive Care Unit, Sackler School of Medicine, Tel Aviv University, Israel.
¹⁷ Universitair Ziekenhuis, Antwerp, Belgium.
¹⁸ Klinik für Anästhesie und allgemeine Intensivmedizin der Universität Wien, Vienna, Austria.
¹⁹ Malignant Hyperthermia Centre, Discipline of Anaesthesia, Pain, and Intensive Care, Universidade Federal de São Paulo, São Paulo, Brazil.
²⁰ MH Unit, Department of Children's Anaesthesiology and PICU, University Hospital Brno, Czech Republic.
²¹ San Antonio General Hospital, Padua, Italy.

PMID: 39482150
DOI: 10.1016/j.bja.2024.09.022

No abstract available

Keywords: activated charcoal filters; dantrolene; guidelines; hyperkalaemia; inhalation anaesthetics; malignant hyperthermia; rhabdomyolysis; succinylcholine.

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Recognition and management of a malignant hyperthermia crisis: updated 2024 guideline from the European Malignant Hyperthermia Group

Collaborators

Affiliations

Recognition and management of a malignant hyperthermia crisis: updated 2024 guideline from the European Malignant Hyperthermia Group

Authors

Collaborators

Affiliations

Publication types

LinkOut - more resources

Full Text Sources