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. 2023 Nov 24;57(11):34-40.
doi: 10.47895/amp.vi0.6256. eCollection 2023.

Adherence of Physicians to Local Guideline Recommendations among Patients with COVID-19 in Two Tertiary Public Hospitals in Metro Manila, Philippines: A Rapid Assessment Study

Affiliations

Adherence of Physicians to Local Guideline Recommendations among Patients with COVID-19 in Two Tertiary Public Hospitals in Metro Manila, Philippines: A Rapid Assessment Study

Anton G Elepaño et al. Acta Med Philipp. .

Abstract

Objectives: Adherence to clinical practice guidelines (CPG) has been shown to reduce inter-physician practice variation and improve quality of care. This study evaluated guideline adherence of physicians in two tertiary public hospitals to local CPG on COVID-19.

Methods: This was a multicenter, retrospective chart review, rapid assessment method study. Guideline adherence and non-adherence (overuse and underuse) to 15 strong recommendations in the prevailing Philippine COVID-19 Living Recommendations were assessed among a sample of patients admitted in two centers from July to October 2021. Differences in adherence across COVID-19 disease severities and managing hospital units were analyzed.

Results: A total of 723 patient charts from two centers were reviewed. Guideline adherence to dexamethasone use among patients with hypoxemia is 91.4% (95% CI 88.6 to 93.6) with 9.2% overuse. Tocilizumab was underused in 52.2% of patients with indications to receive the drug. There was overuse of empiric antibiotics in 43.6% of patients without suspicion of bacterial coinfection. Lowest adherence to antibiotic use was seen among patients with critical disease severity and those managed in the intensive care unit. None of the other non-recommended treatment modalities were given.

Conclusion: Management of COVID-19 in both centers was generally adherent to guideline recommendations. We detected high underuse of tocilizumab probably related to the global supply shortage during the study period and high overuse of antibiotics in patients without suspicion of bacterial coinfection. While the results of this study cannot be generalized in other healthcare settings, we recommend the application of similar rapid assessment studies in guideline adherence evaluation as a quality improvement tool and to identify issues with resource utilization especially during public health emergencies.

Keywords: COVID-19; guideline adherence; quality improvement; rapid assessment.

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Conflict of interest statement

All authors declared no conflicts of interest.

References

    1. Margo CE. Quality care and practice variation: the roles of practice guidelines and public profiles. Surv Ophthalmol. 2004. May-Jun;49(3):359-71. doi: 10.1016/j.survophthal.2004.02.010. - DOI - PubMed
    1. Engel J, Damen NL, van der Wulp I, de Bruijne MC, Wagner C. Adherence to cardiac practice guidelines in the management of non ST-elevation acute coronary syndromes: a systematic literature review. Curr Cardiol Rev. 2017. Feb;13(1):3-27. doi: 10.2174/1573403x12666160404100025. - DOI - PMC - PubMed
    1. Wilke M, Grube RF, Bodmann KF. Guideline-adherent initial intravenous antibiotic therapy for hospital-acquired/ventilator-associated pneumonia is clinically superior, saves lives and is cheaper than non guideline adherent therapy. Eur J Med Res. 2011. Jul;16(7):315-23. doi: 10.1186/2047-783x-16-7-315. - DOI - PMC - PubMed
    1. Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, et al. . Why don’t physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999. Oct;;282(15):1458-65. doi: 10.1001/jama.282.15.1458. - DOI - PubMed
    1. Gangopadhyay KK, Sinha B, Ghosal S. Compliance of the Indian National Task Force guidelines for COVID-19 recommendation by Indian doctors–A survey. Diabetes Metab Syndr. 2020. SepOct;14(5):1413-8. doi: 10.1016/j.dsx.2020.07.040. - DOI - PMC - PubMed