Review
doi: 10.1007/BF00254733.
Retinoids and cancer
- PMID: 394876
- DOI: 10.1007/BF00254733
Item in Clipboard
Review
Retinoids and cancer
Cancer Chemother Pharmacol.
1979.
Abstract
The early and recent investigations in the field of retinoids and cancer are reviewed. The retinoids, including natural vitamin A compounds and their synthetic analogs, present a new class of substances exerting a prophylactic and a therapeutic effect both in certain experimental tumor models and in certain clinical conditions of preneoplastic and neoplastic lesions. Because of a particular physiological mechanism of action, the retinoids offer a new approach to the cancer problem, which is different from those of surgery, X-ray therapy, conventional chemotherapy, and immunotherapy.
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