Effects of human menstrual cycle on thermoregulatory vasodilation during exercise

Abstract

To investigate the effects of the menstrual cycle and of exercise intensity on the relationship between finger blood flow (FBF) and esophageal temperature (Tes), we studied four women, aged 20-32 years. Subjects exercised at 40% and 70% VO2max in the semi-supine posture at an ambient temperature of 20 degrees C. Resting Tes was higher during the luteal phase than the follicular phase (P less than 0.01). There were no significant differences between the two phases in FBF, oxygen consumption, carbon dioxide production, heart rate or minute ventilation at rest and during exercise, respectively. Each regression line of the FBF-Tes relationship consists of two distinct segments of FBF change to Tes (slope 1 and 2). FBF increased at a threshold Tes for vasodilation ([Tes 0]) and the rate of FBF rise became greater at ([Tes 0]) and the rate of FBF rise became greater at another Tes above this threshold ([Tes 0']). For both levels of exercise, [Tes 0] and [Tes 0'] were shifted upward during the luteal phase, but the slopes of the FBF-Tes relationship were almost the same in the two phases of the menstrual cycle. Increasing exercise intensity induced a significant decrease in slope 1 of the FBF-Tes relationship during the follicular (P less than 0.01) and the luteal phases (P less than 0.02), respectively.(ABSTRACT TRUNCATED AT 250 WORDS)