Combined brain and spinal FDG PET in the differentiation between ALS and ALS mimics - correction and additional validation study

Donatienne Van Weehaeghe^{1

2}, Martijn Devrome¹, Joke de Vocht³, Pegah Masrori⁴, Georg Schramm¹, Wies Deckers⁵, Kristof Baete^{1

5}, Caro De Weerdt¹, Philip Van Damme³, Michel Koole¹, Koen Van Laere^{6

7}

Affiliations

¹ Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, 3000, Belgium.
² University Hospital Gent, Gent, 9000, Belgium.
³ Neurology, University Hospital Leuven, Leuven, 3000, Belgium.
⁴ Department of Neuroscience, KU Leuven, Leuven, 3000, Belgium.
⁵ Division of Nuclear Medicine, University Hospital Leuven, Herestraat 49, Leuven, 3000, Belgium.
⁶ Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, 3000, Belgium. Koen.vanlaere@kuleuven.be.
⁷ Division of Nuclear Medicine, University Hospital Leuven, Herestraat 49, Leuven, 3000, Belgium. Koen.vanlaere@kuleuven.be.

Donatienne Van Weehaeghe et al. Eur J Nucl Med Mol Imaging. 2024 Dec.

. 2024 Dec;52(1):109-112.

doi: 10.1007/s00259-024-06957-7. Epub 2024 Nov 4.

¹ Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, 3000, Belgium.
² University Hospital Gent, Gent, 9000, Belgium.
³ Neurology, University Hospital Leuven, Leuven, 3000, Belgium.
⁴ Department of Neuroscience, KU Leuven, Leuven, 3000, Belgium.
⁵ Division of Nuclear Medicine, University Hospital Leuven, Herestraat 49, Leuven, 3000, Belgium.
⁶ Nuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, 3000, Belgium. Koen.vanlaere@kuleuven.be.
⁷ Division of Nuclear Medicine, University Hospital Leuven, Herestraat 49, Leuven, 3000, Belgium. Koen.vanlaere@kuleuven.be.

No abstract available

Conflict of interest statement

Declarations. Competing interests: The authors declare that they have no competing interests.

1. Van Weehaeghe D, Devrome M, Schramm G, De Vocht J, Deckers W, Baete K, et al. Combined brain and spinal FDG PET allows differentiation between ALS and ALS mimics. Eur J Nucl Med Mol Imaging. 2020;47:2681–90. - DOI - PubMed
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1. Marini C, Morbelli S, Cistaro A, Campi C, Caponnetto C, Bauckneht M, et al. Interplay between spinal cord and cerebral cortex metabolism in amyotrophic lateral sclerosis. Brain. 2018;141:2272–9. - DOI - PubMed - PMC