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Review
. 2024 Nov;24(6):100258.
doi: 10.1016/j.clinme.2024.100258. Epub 2024 Oct 25.

Malaria: Past, present and future

Jo Salkeld  1 , Andrew Duncan  2 , Angela M Minassian  2
Affiliations
Review

Malaria: Past, present and future

Jo Salkeld et al. Clin Med (Lond). 2024 Nov.

Abstract

Malaria remains a major global health problem. Transmission occurs in 84 countries across five continents, with almost 250 million cases and over 600,000 deaths each year. Primary and secondary care clinicians in the UK need to be alert to the prospect of malaria presenting in returning travellers. They must be aware of the signs of severe malaria, the need for prompt diagnosis and treatment, and the importance of seeking specialist advice. With emerging resistance, climate change and the roll-out of the first malaria vaccines, the landscape of malaria is changing. Here we discuss the past, present and future of malaria.

Keywords: Fever in returning traveller; Malaria; Tropical medicine.

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Conflict of interest statement

Declaration of competing interest Angela M Minassian has an immediate family member who is an inventor on patent applications relating to RH5 malaria vaccines. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig 1:
Fig. 1
Annual number of UK imported malaria cases (1998–2023). Adapted from UK Health Security Agency data.
See this image and copyright information in PMC

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