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. 1986;224(2):106-9.
doi: 10.1007/BF02141479.

The generation of dense granules within cultured human retinal pigment epithelial cells at senescence

The generation of dense granules within cultured human retinal pigment epithelial cells at senescence

M Boulton et al. Graefes Arch Clin Exp Ophthalmol. 1986.

Abstract

Human retinal pigment epithelial cells routinely lose all forms of pigmentary inclusion when cultured. We report the repigmentation of a senescent population of cells. The pigmented inclusions were found to be neither melanin or lipofuscin but some form of dense membranous lamellae.

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