Perianal Crohn's disease: Still more questions than answers
- PMID: 39492828
- PMCID: PMC11525859
- DOI: 10.3748/wjg.v30.i39.4260
Perianal Crohn's disease: Still more questions than answers
Abstract
In this editorial we comment on the article by Pacheco et al published in a recent issue of the World Journal of Gastroenterology. We focus specifically on the burden of illness associated with perianal fistulizing Crohn's disease (PFCD) and the diagnostic and therapeutic challenges in the management of this condition. Evolving evidence has shifted the diagnostic framework for PFCD from anatomical classification systems, to one that is more nuanced and patient-focused to drive ongoing decision making. This editorial aims to reflect on these aspects to help clinicians face the challenge of PFCD in day-to-day clinical practice.
Keywords: Anorectal malignancy; Crohn’s disease classification; Crohn’s disease treatment; Disease severity; Perianal Crohn’s disease.
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
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References
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- Adegbola SO, Dibley L, Sahnan K, Wade T, Verjee A, Sawyer R, Mannick S, McCluskey D, Yassin N, Phillips RKS, Tozer PJ, Norton C, Hart AL. Burden of disease and adaptation to life in patients with Crohn's perianal fistula: a qualitative exploration. Health Qual Life Outcomes. 2020;18:370. - PMC - PubMed
-
- Atia O, Asayag N, Focht G, Lujan R, Ledder O, Greenfeld S, Kariv R, Dotan I, Gabay H, Balicer R, Haklai Z, Nevo D, Turner D. Perianal Crohn's Disease Is Associated With Poor Disease Outcome: A Nationwide Study From the epiIIRN Cohort. Clin Gastroenterol Hepatol. 2022;20:e484–e495. - PubMed
-
- Attauabi M, Burisch J, Seidelin JB. Efficacy of ustekinumab for active perianal fistulizing Crohn's disease: a systematic review and meta-analysis of the current literature. Scand J Gastroenterol. 2021;56:53–58. - PubMed
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