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Case Reports
. 2024 Oct 3;16(10):e70746.
doi: 10.7759/cureus.70746. eCollection 2024 Oct.

A Rare Presentation of Myoepithelioma of the Parotid Gland Manifesting as an Infra-Auricular Swelling

Yash Kalra  1 , Saahiti Koppolu  1 , Manu Babu  1 , Rashmi Prashant  1 , Akshi Raj  2 , Mayur Ingale  1
Affiliations
Case Reports

A Rare Presentation of Myoepithelioma of the Parotid Gland Manifesting as an Infra-Auricular Swelling

Yash Kalra et al. Cureus. .

Abstract

This report describes an uncommon tumor of the salivary glands, myoepithelioma, that primarily affects major and minor glands, with a notable predilection for the parotid gland. Typically benign, this tumor arises from aberrant myoepithelial cells situated between the basement membrane and acinar cells. Myoepitheliomas are considered a subset of pleomorphic adenomas, distinguished by excessive myoepithelial cell growth. Despite their initial discovery, the precise histopathological and immunohistochemical characteristics of these tumors remain elusive, posing a diagnostic challenge because of their complex nature. We discuss a case of a 42-year-old female who had a 2 x 2 cm lump in the right infra-auricular area. The lump was examined with ultrasonography (USG) and later surgically removed. The initial frozen section analysis indicated an oncocytic lesion, but further histopathological and immunohistochemical evaluations confirmed that it was a myoepithelioma of the parotid gland.

Keywords: benign parotid tumors; myoepithelioma; parotid myoepithelioma; rare case report; unusual presentation.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Preoperative images showing the swelling on the right lateral aspect of neck
A: Right lateral profile with the arrow denoting the swelling. B: Central profile with the arrow denoting the swelling. C: Left lateral profile
Figure 2
Figure 2. Intraoperative images
A: White arrow denoting the excised specimen sent for histopathological examination. B: White arrow denoting the right parotid region post-excision
Figure 3
Figure 3. Postoperative image showing the surgical site closed with prolene sutures
Figure 4
Figure 4. Histopathological images of the excised specimen
A: Hematoxylin and eosin stain, 100x magnification: the whole field shows cells arranged in sheets with the arrows marking eosinophilic acellular areas in the stroma. B: Hematoxylin and eosin stain, 400x magnification: black arrows without fill marking eosinophilic acellular areas in stroma; white solid fill arrows marking round to polygonal cells with central to eccentric nuclei and eosinophilic granular cytoplasm
See this image and copyright information in PMC

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