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Review
. 2024;14(6):29968.
doi: 10.34172/bi.2024.29968. Epub 2024 Mar 12.

COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis

Elina Armani Khatibi  1 , Nastaran Farshbaf Moghimi  1 , Elaheh Rahimpour  2
Affiliations
Review

COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis

Elina Armani Khatibi et al. Bioimpacts. 2024.

Abstract

COVID-19 is an RNA virus belonging to the SARS family of viruses and includes a wide range of symptoms along with effects on other body organs in addition to the respiratory system. The high speed of transmission, severe complications, and high death rate caused scientists to focus on this disease. Today, many different investigation types are performed on COVID-19 from various points of view in the literature. This review summarizes most of them to provide a useful guideline for researchers in this field. After a general introduction, this review is divided into three parts. In the first one, various transmission ways COVID-19 are classified and explained in detail. The second part reviews the used biological samples for the detection of virus and the final section describes the various methods reported for the diagnosis of COVID-19 in various biological matrices.

Keywords: COVID-19; Detection methods; Infection; Sampling; Transmission.

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Conflict of interest statement

The authors declare no conflict of interest.

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References

    1. Ciotti M, Ciccozzi M, Terrinoni A, Jiang W-C, Wang C-B, Bernardini S. The COVID-19 pandemic. Crit Rev Clin Lab Sci. 2020;57:365–88. doi: 10.1080/10408363.2020.1783198. - DOI - PubMed
    1. Jacob CO. On the genetics and immunopathogenesis of COVID-19. Clin Immunol. 2020;220:108591. doi: 10.1016/j.clim.2020.108591. - DOI - PMC - PubMed
    1. Li W, Sui J, Huang I-C, Kuhn JH, Radoshitzky SR, Marasco WA, et al. The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2. Virology. 2007;367:367–74. doi: 10.1016/j.virol.2007.04.035. - DOI - PMC - PubMed
    1. Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; 181: 271-80.e8. 10.1016/j.cell.2020.02.052. - DOI - PMC - PubMed
    1. Walls AC, Park Y-J, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein. Cell 2020; 181: 281-92. e6. 10.1016/j.cell.2020.02.058. - DOI - PMC - PubMed

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