Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Apr 4:17:e03.
doi: 10.15420/usc.2022.26. eCollection 2023.

Mechanical Circulatory Support for Complex High-risk Percutaneous Coronary Intervention

Alexander G Truesdell  1   2 , Rhian Davies  3 , Moemen Eltelbany  2 , Michael Megaly  4 , Carolyn Rosner  2 , Lindsey A Cilia  1   2
Affiliations
Review

Mechanical Circulatory Support for Complex High-risk Percutaneous Coronary Intervention

Alexander G Truesdell et al. US Cardiol. .

Abstract

Technological and procedural innovations presently permit the safe and effective performance of increasingly complex percutaneous coronary interventions, while new mechanical circulatory support devices offer circulatory and ventricular support to patients with severely reduced left ventricular systolic function and deranged cardiovascular hemodynamics. Together, these advances now permit the application of complex percutaneous coronary interventions to higher-risk patients who might otherwise be left untreated. Increasing observational data support the use of mechanical circulatory support in appropriate complex and high-risk patients as part of a larger multidisciplinary heart team treatment plan. In-progress and upcoming randomized clinical trials may provide higher-quality evidence to better guide management decisions in the near future.

Keywords: Mechanical circulatory support; complex and high-risk; percutaneous coronary intervention.

PubMed Disclaimer

Conflict of interest statement

Disclosure: AGT has received consultancy and speakers fees from Abiomed and Shockwave Medical. RD has recevied consultancy and speakers fees from Abiomed, Asahi Intec, Biotronik, Boston Scientific, Medtronic, Siemens Healthcare, and Shockwave Medical. All other authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Decision-making for Mechanical Circulatory Support Use in Complex High-risk Percutaneous Coronary Interventions
Figure 2:
Figure 2:. Mechanical Circulatory Support Devices for Complex High-risk Coronary Intervention
Figure 3:
Figure 3:. Complications of Mechanical Circulatory Support Use in Complex High-risk Coronary Intervention
See this image and copyright information in PMC

References

    1. Riley RF, Henry TD, Mahmud E et al. SCAI position statement on optimal percutaneous coronary interventional therapy for complex coronary artery disease. Catheter Cardiovasc Interv. 2020;96:346–62. doi: 10.1002/ccd.28994. - DOI - PubMed
    1. Lincoff AM, Popma JJ, Ellis SG et al. Percutaneous support devices for high risk or complicated coronary angioplasty. J Am Coll Cardiol. 1991;17:770–80. doi: 10.1016/s0735-1097(10)80197-4. - DOI - PubMed
    1. Hannan EL, Racz M, Holmes DR et al. Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent era. Circulation. 2006;113:2406–12. doi: 10.1161/CIRCULATIONAHA.106.612267. - DOI - PubMed
    1. Kirtane AJ, Doshi D, Leon MB et al. Treatment of higher-risk patients with an indication for revascularization: evolution within the field of contemporary percutaneous coronary intervention. Circulation. 2016;134:422–31. doi: 10.1161/CIRCULATIONAHA.116.022061. - DOI - PMC - PubMed
    1. Kent KM, Bentivoglio LG, Block PC et al. Percutaneous transluminal coronary angioplasty: report from the Registry of the National Heart, Lung, and Blood Institute. Am J Cardiol. 1982;49:2011–20. doi: 10.1016/0002-9149(82)90223-5. - DOI - PubMed

LinkOut - more resources