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Review
. 2024 Nov 4.
doi: 10.1111/pace.15101. Online ahead of print.

Coronary Spasm Due to Pulsed Field Ablation: A State-of-the-Art Review

Affiliations
Review

Coronary Spasm Due to Pulsed Field Ablation: A State-of-the-Art Review

David A Ramirez et al. Pacing Clin Electrophysiol. .

Abstract

With the ever-growing population of patients undergoing cardiac ablation with pulsed electric fields, there is a need to understand secondary effects from the therapy. Coronary artery spasm is one such effect that has recently emerged as the subject of further investigation in electrophysiology literature. This review aims to elucidate the basic anatomy underlying vascular spasm due to pulsed electric fields and the effects of irreversible electroporation on coronary arteries. This review also aims to gather the current preclinical and clinical data regarding the physiology and function of coronary arteries following electroporation.

Keywords: coronary spasm; irreversible electroporation; pulsed field ablation; vascular smooth muscle.

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References

    1. G. Vetta, D. G. Della Rocca, L. Pannone, et al., “First Multicenter Experience of Pulmonary Vein and Posterior Wall Isolation Via a Novel Focal 9mm Lattice Tip Catheter in a Real‐World Scenario,” supplement, EP Europace 26, no. S1 (2024): euae102.193, https://academic.oup.com/europace/article/26/Supplement_1/euae102.193/76....
    1. E. Ekanem, V. Y. Reddy, B. Schmidt, et al., “Multi‐National Survey on the Methods, Efficacy, and Safety on the Post‐Approval Clinical Use of Pulsed Field Ablation (MANIFEST‐PF),” Europace 24, no. 8 (2022): 1256–1266.
    1. M. Duytschaever, T. De Potter, M. Grimaldi, et al., “Paroxysmal Atrial Fibrillation Ablation Using a Novel Variable‐Loop Biphasic Pulsed Field Ablation Catheter Integrated With a 3‐Dimensional Mapping System: 1‐Year Outcomes of the Multicenter inspIRE Study,” Circulation: Arrhythmia and Electrophysiology 16 , no. 3 (2023): e011780.
    1. V. Y. Reddy, P. Peichl, E. Anter, et al., “A Focal Ablation Catheter Toggling Between Radiofrequency and Pulsed Field Energy to Treat Atrial Fibrillation,” JACC: Clinical Electrophysiology 9 , no. 8 pt. 3 (2023): 1786–1801.
    1. A. Verma, D. E. Haines, L. V. Boersma, et al., “Pulsed Field Ablation for the Treatment of Atrial Fibrillation: PULSED AF Pivotal Trial,” Circulation 147, no. 19 (2023): 1422–1432, https://doi.org/10.1161/CIRCULATIONAHA.123.063988.

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