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. 2025 Apr;49(7):1797-1807.
doi: 10.1007/s00266-024-04482-4. Epub 2024 Nov 4.

Facial Rejuvenation Strategy in Asian Women with Autologous Fat Transplantation

Jianhui Zhao #  1 , Chen Chen #  2 , Xiao Dong Lan  3 , Xiao Qin  4 , Dan Li  4 , Yan Zheng  5
Affiliations

Facial Rejuvenation Strategy in Asian Women with Autologous Fat Transplantation

Jianhui Zhao et al. Aesthetic Plast Surg. 2025 Apr.

Abstract

Objective: To explore the clinical strategy of autologous fat transplantation in facial rejuvenation.

Methods: From September 2016 to May 2023, 2715 female patients with facial filling by autologous fat were retrospectively analysed. After treatment, they were followed up for 3-6 months to summarize the relationship between aesthetic design and treatment outcomes.

Results: In total, 2306 patients were followed up and completed the questionnaires of satisfactory. Most patients (97%, 2237 cases) achieved satisfactory results after one operation, and about 3% (69 cases) achieved satisfactory results after secondary filling.

Conclusion: Autologous fat granule transplantation in the treatment of facial rejuvenation can achieve an excellent therapeutic outcome. Customized design according to the different lineaments, age, and other factors, and extensive use of various treatment methods can achieve better results.

Level of evidence iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Keywords: Aesthetic design; Autologous fat transplantation; Collagen fibres in subcutaneous fat (CFSF); Lineament reconstruction; Rejuvenation.

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Conflict of interest statement

Declarations. Conflict of interest: The other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Ethical Approval: This retrospective study was conducted in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments. The need for formal ethical approval was waived by the institutional ethics committee due to the retrospective nature of the study and the use of de-identified patient data. Informed Consent: All patients included in this study signed informed consent forms prior to undergoing the autologous fat transplantation procedure.

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