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. 1986 Feb 25;261(6):2496-8.

Availability of hyperacetylated H4 histone in intact nucleosomes to specific antibodies

  • PMID: 3949730
Free article

Availability of hyperacetylated H4 histone in intact nucleosomes to specific antibodies

U Pfeffer et al. J Biol Chem. .
Free article

Abstract

Specific antibodies against the tetra-acetylated form of H4 histone have been elicited in the rabbit. They do not cross-react with the non-, mono-, and di-acetylated forms of the histone molecule but a slight cross-reactivity with the tri-acetylated form of H4 histone is observed. Our studies also show that hyperacetylated H4 histones are recognized by the antibodies in intact nucleosomes.

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