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. 2024 Oct 2;7(6):423-426.
doi: 10.1002/iju5.12761. eCollection 2024 Nov.

Cranial neuropathy following coronavirus disease 2019 vaccination in kidney transplant recipients

Shota Fukae  1 , Kazuaki Yamanaka  1 , Soichi Matsumura  1 , Ryo Tanaka  1 , Shigeaki Nakazawa  1 , Yoichi Kakuta  1 , Norio Nonomura  1
Affiliations

Cranial neuropathy following coronavirus disease 2019 vaccination in kidney transplant recipients

Shota Fukae et al. IJU Case Rep. .

Abstract

Introduction: Understanding of adverse reactions to coronavirus disease 2019 vaccines remains limited.

Case presentation: Case 1: A 52-year-old woman, post-kidney transplantation, experienced sudden vision loss in her left eye after receiving a second dose of coronavirus disease 2019 vaccine. She was diagnosed with ischemic optic neuropathy.Case 2: A 53-year-old woman, post-kidney transplantation, presented with worsening diplopia and left eye pain following the second dose of coronavirus disease 2019 vaccine. She was diagnosed with left abducens nerve palsy.

Conclusion: Vigilance is essential for recognizing the potential for delayed cranial neuropathy in immunocompromised individuals after coronavirus disease 2019 vaccination.

Keywords: COVID‐19; COVID‐19 vaccine; cranial neuropathy; infection; kidney transplantation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Fundoscopy: Fundoscopy shows hemorrhage and edema in the optic papilla (arrow), in the left eye (a, right eye: b, left eye).
Fig. 2
Fig. 2
SARS‐CoV‐2 antibody titer: No increase in anti‐COVID‐19 antibody titers observed in case 1 but increased from the third dose in case 2 (a, case 1: b, case 2).
See this image and copyright information in PMC

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References

    1. Hardgrave H, Wells A, Nigh J et al. COVID‐19 mortality in vaccinated vs. unvaccinated liver & kidney transplant recipients: a single‐center United States propensity score matching study on historical data. Vaccine 2022; 10: 1921. - PMC - PubMed
    1. Efros O, Anteby R, Halfon M, Meisel E, Klang E, Soffer S. Efficacy and safety of third dose of the COVID‐19 vaccine among solid organ transplant recipients: a systemic review and meta‐analysis. Vaccine 2022; 10: 95. - PMC - PubMed
    1. Holm MR, Poland GA. Critical aspects of packaging, storage, preparation, and administration of mRNA and adenovirus‐vectored COVID‐19 vaccines for optimal efficacy. Vaccine 2021; 39: 457–459. - PMC - PubMed
    1. Hayreh SS. Ischemic optic neuropathy. Prog. Retin. Eye Res. 2009; 28: 34–62. - PubMed
    1. Tsukii R, Kasuya Y, Makino S. Nonarteritic anterior ischemic optic neuropathy following COVID‐19 vaccination: consequence or coincidence. Case Rep. Ophthalmol. Med. 2021; 2021: 5126254. - PMC - PubMed

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