The Fourth Annual Symposium of the Midwest Aging Consortium

Jinoh Kim¹, Rochelle Buffenstein², Anne M Bronikowski^{3

4}, Natalia-Del Pilar Vanegas^{5

6}, Lorena Rosas^{5

6}, Paula Agudelo-Garcia^{5

6}, Ana L Mora^{5

6}, Mauricio Rojas^{5

6}, Davis A Englund^{7

8}, Nathan K LeBrasseur^{7

9}, Allancer Nunes¹⁰, Paul D Robbins¹⁰, Marian L Kohut^{4

11}, Siddhant Kothadiya^{4

12}, Rizia Bardhan^{4

12}, Christina D Camell^{10

13}, Ines Sturmlechner^{7

14}, Jörg J Goronzy^{7

14}, Chung-Yang Yeh^{15

16}, Dudley W Lamming^{15

16}, Shijiao Huang^{17

18}, Scott F Leiser^{17

19}, Wilber Escorcia²⁰, Matthew S Gill^{10

21}, Jackson R Taylor^{22

23}, Stephen L Helfand²², Sovannarith Korm²⁴, Kristin E Gribble²⁴, Mariana Pehar^{15

25}, Magdalena Blaszkiewicz²⁶, Kristy L Townsend²⁶, Eric R McGregor^{15

27}, Rozalyn M Anderson^{15

25}, Lukas Stilgenbauer²⁸, Marianna Sadagurski^{28

29}, Alicia Taylor^{30

31}, Elizabeth McNeill^{30

31}, Thomas Stoeger^{32

33}, Hua Bai¹

Affiliations

¹ Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, USA.
² Department of Biological Science, University of Illinois at Chicago, Chicago, Illinois, USA.
³ Department of Integrative Biology, Michigan State University, East Lansing, Michigan, USA.
⁴ Nanovaccine Institute, Iowa State University, Ames, Iowa, USA.
⁵ Division of Pulmonary, Critical Care and Sleep Medicine, Davis Heart Lung, Research Institute, Columbus, Ohio, USA.
⁶ Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
⁷ Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
⁸ Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
⁹ Paul F. Glenn Center for the Biology of Aging at Mayo Clinic, Rochester, Minnesota, USA.
¹⁰ Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, Minnesota, USA.
¹¹ Department of Kinesiology, Iowa State University, Ames, Iowa, USA.
¹² Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, USA.
¹³ Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
¹⁴ Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.
¹⁵ Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
¹⁶ William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.
¹⁷ Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
¹⁸ Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
¹⁹ Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
²⁰ Department of Biology, Xavier University, Cincinnati, Ohio, USA.
²¹ Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA.
²² Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
²³ Center for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
²⁴ The Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts, USA.
²⁵ Geriatric Research Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.
²⁶ Department of Neurological Surgery, The Ohio State University, Columbus, Ohio, USA.
²⁷ Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
²⁸ Department of Biological Sciences, Integrative Biosciences Center, Wayne State University, Detroit, Michigan, USA.
²⁹ Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, Michigan, USA.
³⁰ Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
³¹ Neuroscience Interdepartmental Graduate Program, Iowa State University, Ames, Iowa, USA.
³² Division of Pulmonary and Critical Care, Northwestern University, Chicago, Illinois, USA.
³³ The Potocsnak Longevity Institute, Northwestern University, Chicago, Illinois, USA.

PMID: 39498863
PMCID: PMC11536180
DOI: 10.1093/gerona/glae236

The Fourth Annual Symposium of the Midwest Aging Consortium

Jinoh Kim et al. J Gerontol A Biol Sci Med Sci. 2024.

. 2024 Nov 1;79(11):glae236.

doi: 10.1093/gerona/glae236.

Authors

Affiliations

¹ Department of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, USA.
² Department of Biological Science, University of Illinois at Chicago, Chicago, Illinois, USA.
³ Department of Integrative Biology, Michigan State University, East Lansing, Michigan, USA.
⁴ Nanovaccine Institute, Iowa State University, Ames, Iowa, USA.
⁵ Division of Pulmonary, Critical Care and Sleep Medicine, Davis Heart Lung, Research Institute, Columbus, Ohio, USA.
⁶ Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
⁷ Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
⁸ Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
⁹ Paul F. Glenn Center for the Biology of Aging at Mayo Clinic, Rochester, Minnesota, USA.
¹⁰ Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, Minnesota, USA.
¹¹ Department of Kinesiology, Iowa State University, Ames, Iowa, USA.
¹² Department of Chemical and Biological Engineering, Iowa State University, Ames, Iowa, USA.
¹³ Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
¹⁴ Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.
¹⁵ Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
¹⁶ William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.
¹⁷ Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
¹⁸ Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas, USA.
¹⁹ Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
²⁰ Department of Biology, Xavier University, Cincinnati, Ohio, USA.
²¹ Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA.
²² Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island, USA.
²³ Center for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
²⁴ The Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, Massachusetts, USA.
²⁵ Geriatric Research Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.
²⁶ Department of Neurological Surgery, The Ohio State University, Columbus, Ohio, USA.
²⁷ Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
²⁸ Department of Biological Sciences, Integrative Biosciences Center, Wayne State University, Detroit, Michigan, USA.
²⁹ Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, Michigan, USA.
³⁰ Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
³¹ Neuroscience Interdepartmental Graduate Program, Iowa State University, Ames, Iowa, USA.
³² Division of Pulmonary and Critical Care, Northwestern University, Chicago, Illinois, USA.
³³ The Potocsnak Longevity Institute, Northwestern University, Chicago, Illinois, USA.

PMID: 39498863
PMCID: PMC11536180
DOI: 10.1093/gerona/glae236

Abstract

The Midwest Aging Consortium (MAC) has emerged as a critical collaborative initiative aimed at advancing our understanding of aging and developing strategies to combat the rising prevalence of age-related diseases. Founded in 2019, MAC brings together researchers from various disciplines and institutions across the Midwestern United States to foster interdisciplinary geroscience research. This report summarizes the highlights of the Fourth Annual Symposium of MAC, which was held at Iowa State University in May 2023. The symposium featured presentations on a wide array of topics, including studies on slow-aging animals, cellular senescence and senotherapeutics, the role of the immune system in aging, metabolic changes in aging, neuronal health in aging, and biomarkers for measuring the aging process. Speakers shared findings from studies involving a variety of animals, ranging from commonly used species such as mice, rats, worms, yeast, and fruit flies, to less-common ones like naked mole-rats, painted turtles, and rotifers. MAC continues to emphasize the importance of supporting emerging researchers and fostering a collaborative environment, positioning itself as a leader in aging research. This symposium not only showcased the current state of aging biology research but also highlighted the consortium's role in training the next generation of scientists dedicated to improving the healthspan and well-being of the aging population.

Keywords: Aging; Biomarker; Gerontology; Immunity; Metabolism; Senescence.

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Conflict of interest statement

D.W.L has received funding from, and is a scientific advisory board member of, Aeovian Pharmaceuticals, which seeks to develop novel, selective mTOR inhibitors for the treatment of various diseases. The other authors declare no conflict.

References

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The Fourth Annual Symposium of the Midwest Aging Consortium

Affiliations

The Fourth Annual Symposium of the Midwest Aging Consortium

Authors

Affiliations

Abstract

Conflict of interest statement

References

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Medical