Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Jan 1;47(1):42-45.
doi: 10.1097/DAD.0000000000002883. Epub 2024 Nov 5.

Extradigital Symplastic Glomus Tumor and Review of the Literature

Eva B Niklinska  1 , Jonathan Miller  2 , Jeffrey P Zwerner  1   3 , Alan S Boyd  1   3
Affiliations
Review

Extradigital Symplastic Glomus Tumor and Review of the Literature

Eva B Niklinska et al. Am J Dermatopathol. .

Abstract

Symplastic glomus tumors are a rare subtype of glomus tumor defined by nuclear atypia without additional markers of malignancy such as large size, deep location, or atypical/prevalent mitotic figures. Glomus tumors, including the symplastic subtype, most commonly present in the subungual area with rarer extradigital presentation. To our knowledge, there have been less than 25 cases of symplastic glomus tumors described in the literature. Herein, we present a case of extradigital symplastic glomus tumor with review of the literature.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

References

    1. Chong Y, Eom M, Min H-J, et al. Symplastic glomus tumor: a case report. Am J Dermatopathol. 2009;31:71–73.
    1. Kamarashev J, French LE, Dummer R, et al. Symplastic glomus tumor–a rare but distinct benign histological variant with analogy to other ‘ancient’benign skin neoplasms. J Cutan Pathol. 2009;36:1099–1102.
    1. Wang Y, Xiang Y, Bian Y, et al. Glomus tumors associated with the bone and joints: a review of 91 cases. Ann Transl Med. 2020;8:1460.
    1. Schiefer TK, Parker WL, Anakwenze OA, et al. Extradigital Glomus Tumors: A 20-year Experience. Elsevier; 2006:1337–1344.
    1. Kang G, Park HJ, Kim JY, et al. Glomus tumor of the stomach: a clinicopathologic analysis of 10 cases and review of the literature. Gut and liver. 2012;6:52–57.

LinkOut - more resources